Office-based dynamic imaging of vocal cords in awake patients with swept-source optical coherence tomography

Lingfeng Yu, Gangjun Liu, Marc Rubinstein, Arya Saidi, Brian J F Wong, Zhongping Chen

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Optical coherence tomography (OCT) is an evolving noninvasive imaging modality that has been used to image the human larynx during surgical endoscopy. The design of a long gradient index (GRIN) lens-based probe capable of capturing images of the human larynx by use of swept-source OCT during a typical office-based laryngoscopy examination is presented. In vivo OCT imaging of the human larynx is demonstrated with a rate of 40 frames per second. Dynamic vibration of the vocal folds is recorded to provide not only high-resolution cross-sectional tissue structures but also vibration parameters, such as the vibration frequency and magnitude of the vocal cords, which provides important information for clinical diagnosis and treatment, as well as fundamental research of the voice itself. Office-based OCT is a promising imaging modality to study the larynx for physicians in otolaryngology.

Original languageEnglish (US)
Article number064020
JournalJournal of Biomedical Optics
Volume14
Issue number6
DOIs
StatePublished - 2009
Externally publishedYes

Fingerprint

vocal cords
larynx
Optical tomography
tomography
Imaging techniques
vibration
otolaryngology
physicians
Endoscopy
Lenses
examination
lenses
Tissue
gradients
probes
high resolution

Keywords

  • Biomedical imaging
  • Early diagnosis
  • Laryngeal cancer
  • Larynx
  • Optical coherence tomography

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

Cite this

Office-based dynamic imaging of vocal cords in awake patients with swept-source optical coherence tomography. / Yu, Lingfeng; Liu, Gangjun; Rubinstein, Marc; Saidi, Arya; Wong, Brian J F; Chen, Zhongping.

In: Journal of Biomedical Optics, Vol. 14, No. 6, 064020, 2009.

Research output: Contribution to journalArticle

Yu, Lingfeng ; Liu, Gangjun ; Rubinstein, Marc ; Saidi, Arya ; Wong, Brian J F ; Chen, Zhongping. / Office-based dynamic imaging of vocal cords in awake patients with swept-source optical coherence tomography. In: Journal of Biomedical Optics. 2009 ; Vol. 14, No. 6.
@article{55a6907316bc43fcbcf4075b4d425cff,
title = "Office-based dynamic imaging of vocal cords in awake patients with swept-source optical coherence tomography",
abstract = "Optical coherence tomography (OCT) is an evolving noninvasive imaging modality that has been used to image the human larynx during surgical endoscopy. The design of a long gradient index (GRIN) lens-based probe capable of capturing images of the human larynx by use of swept-source OCT during a typical office-based laryngoscopy examination is presented. In vivo OCT imaging of the human larynx is demonstrated with a rate of 40 frames per second. Dynamic vibration of the vocal folds is recorded to provide not only high-resolution cross-sectional tissue structures but also vibration parameters, such as the vibration frequency and magnitude of the vocal cords, which provides important information for clinical diagnosis and treatment, as well as fundamental research of the voice itself. Office-based OCT is a promising imaging modality to study the larynx for physicians in otolaryngology.",
keywords = "Biomedical imaging, Early diagnosis, Laryngeal cancer, Larynx, Optical coherence tomography",
author = "Lingfeng Yu and Gangjun Liu and Marc Rubinstein and Arya Saidi and Wong, {Brian J F} and Zhongping Chen",
year = "2009",
doi = "10.1117/1.3268442",
language = "English (US)",
volume = "14",
journal = "Journal of Biomedical Optics",
issn = "1083-3668",
publisher = "SPIE",
number = "6",

}

TY - JOUR

T1 - Office-based dynamic imaging of vocal cords in awake patients with swept-source optical coherence tomography

AU - Yu, Lingfeng

AU - Liu, Gangjun

AU - Rubinstein, Marc

AU - Saidi, Arya

AU - Wong, Brian J F

AU - Chen, Zhongping

PY - 2009

Y1 - 2009

N2 - Optical coherence tomography (OCT) is an evolving noninvasive imaging modality that has been used to image the human larynx during surgical endoscopy. The design of a long gradient index (GRIN) lens-based probe capable of capturing images of the human larynx by use of swept-source OCT during a typical office-based laryngoscopy examination is presented. In vivo OCT imaging of the human larynx is demonstrated with a rate of 40 frames per second. Dynamic vibration of the vocal folds is recorded to provide not only high-resolution cross-sectional tissue structures but also vibration parameters, such as the vibration frequency and magnitude of the vocal cords, which provides important information for clinical diagnosis and treatment, as well as fundamental research of the voice itself. Office-based OCT is a promising imaging modality to study the larynx for physicians in otolaryngology.

AB - Optical coherence tomography (OCT) is an evolving noninvasive imaging modality that has been used to image the human larynx during surgical endoscopy. The design of a long gradient index (GRIN) lens-based probe capable of capturing images of the human larynx by use of swept-source OCT during a typical office-based laryngoscopy examination is presented. In vivo OCT imaging of the human larynx is demonstrated with a rate of 40 frames per second. Dynamic vibration of the vocal folds is recorded to provide not only high-resolution cross-sectional tissue structures but also vibration parameters, such as the vibration frequency and magnitude of the vocal cords, which provides important information for clinical diagnosis and treatment, as well as fundamental research of the voice itself. Office-based OCT is a promising imaging modality to study the larynx for physicians in otolaryngology.

KW - Biomedical imaging

KW - Early diagnosis

KW - Laryngeal cancer

KW - Larynx

KW - Optical coherence tomography

UR - http://www.scopus.com/inward/record.url?scp=77950356900&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950356900&partnerID=8YFLogxK

U2 - 10.1117/1.3268442

DO - 10.1117/1.3268442

M3 - Article

VL - 14

JO - Journal of Biomedical Optics

JF - Journal of Biomedical Optics

SN - 1083-3668

IS - 6

M1 - 064020

ER -