OCT-guided TMR

John A. Viator, Kenton Gregory

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Transmyocardial revascularization (TMR) has been investigated as a means of reperfusing ischemic heart tissue by introducing channels in the myocardium. In percutaneous TMR (P TMR), the channels are made from within the left ventricle by introducing an excimer laser catheter via the femoral artery. There is currently no means of determining the limits of ablation in P TMR so that the epicardium is not perforated. We used an optical coherence tomography (OCT) signal to detect the epicardial surface during excimer laser ablation of the myocardium in porcine hearts. A XeCl excimer laser operating at 308 nm with a pulse duration of 125-200 ns and a pulse energy of 21/mJ at 25 Hz was used to ablate channels in porcine hearts ex vivo. The OCT system was connected to an optical fiber guidewire that was introduced coaxially with the ablation fiber. The OCT signal was monitored on a computer during the ablation process. The epicardial surface was detected within 600 μm of perforation.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSociety of Photo-Optical Instrumentation Engineers
Pages528-535
Number of pages8
Volume3907
StatePublished - 2000
EventLasers in Surgery: Advanced Characterization, Therapeutics, and Systems X - San Jose, CA, USA
Duration: Jan 22 2000Jan 25 2000

Other

OtherLasers in Surgery: Advanced Characterization, Therapeutics, and Systems X
CitySan Jose, CA, USA
Period1/22/001/25/00

Fingerprint

Optical tomography
Excimer lasers
Ablation
excimer lasers
ablation
myocardium
tomography
epicardium
perforation
Catheters
Laser ablation
arteries
laser ablation
Optical fibers
Laser pulses
pulse duration
optical fibers
Tissue
fibers
Fibers

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Viator, J. A., & Gregory, K. (2000). OCT-guided TMR. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3907, pp. 528-535). Society of Photo-Optical Instrumentation Engineers.

OCT-guided TMR. / Viator, John A.; Gregory, Kenton.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3907 Society of Photo-Optical Instrumentation Engineers, 2000. p. 528-535.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Viator, JA & Gregory, K 2000, OCT-guided TMR. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 3907, Society of Photo-Optical Instrumentation Engineers, pp. 528-535, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X, San Jose, CA, USA, 1/22/00.
Viator JA, Gregory K. OCT-guided TMR. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3907. Society of Photo-Optical Instrumentation Engineers. 2000. p. 528-535
Viator, John A. ; Gregory, Kenton. / OCT-guided TMR. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3907 Society of Photo-Optical Instrumentation Engineers, 2000. pp. 528-535
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