Observations on intramembrane charge movements in skeletal muscle.

Wolfhard Almers

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Using signal-averaging techniques, one can record small membrane currents which remain even after blockage of the ionic currents which accompany electrical excitation in muscle. These residual currents probably represent the reorientation of charged molecules inside the membrane in response to a change in membrane potential. Two operationally separable types of intramembrane charge movement in muscle are described, one of which may play a role in excitation-contraction coupling. Studies of tetrodotoxin binding to muscle indicate that "sodium gating current" is unlikely to contribute significantly to either type of charge movement.

Original languageEnglish (US)
Pages (from-to)507-513
Number of pages7
JournalPhilosophical transactions of the Royal Society of London. Series B: Biological sciences
Volume270
Issue number908
StatePublished - Jun 10 1975
Externally publishedYes

Fingerprint

Muscle
skeletal muscle
Skeletal Muscle
muscle
Membranes
Muscles
muscles
membrane
Excitation Contraction Coupling
tetrodotoxin
Tetrodotoxin
membrane potential
Membrane Potentials
Sodium
sodium
contraction
Molecules
methodology

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Agricultural and Biological Sciences (miscellaneous)

Cite this

Observations on intramembrane charge movements in skeletal muscle. / Almers, Wolfhard.

In: Philosophical transactions of the Royal Society of London. Series B: Biological sciences, Vol. 270, No. 908, 10.06.1975, p. 507-513.

Research output: Contribution to journalArticle

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