Observations of cochlear microcirculation using intravital microscopy

Alf Axelsson, Alfred Nuttall, Josef M. Miller

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The guinea pig cochlea was prepared for visual observation of blood vessels using fluorescence intravital microscopic techniques. Measurements were made of the lateral wall vessels in the third cochlear turn and of the basilar membrane and lateral wall vessels in the first turn. A stable and consistent pattern of flow was observed under a variety of manipulations, including blood pressures of less than 20 mmHg. The rationale for the choice of observation areas in the cochlea and the specific vessel types studied at these locations are discussed. The change in blood velocity in cochlear blood vessels during pentoxifylline perfusion and during exsanguination are described.

Original languageEnglish (US)
Pages (from-to)263-270
Number of pages8
JournalActa Oto-Laryngologica
Volume109
Issue number3-4
DOIs
StatePublished - 1990
Externally publishedYes

Fingerprint

Cochlea
Microcirculation
Blood Vessels
Observation
Basilar Membrane
Exsanguination
Pentoxifylline
Guinea Pigs
Perfusion
Fluorescence
Blood Pressure
Intravital Microscopy

Keywords

  • Cochlea
  • Fluorescence intravital microscopy
  • Lateral wall
  • Vessel measurements

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Observations of cochlear microcirculation using intravital microscopy. / Axelsson, Alf; Nuttall, Alfred; Miller, Josef M.

In: Acta Oto-Laryngologica, Vol. 109, No. 3-4, 1990, p. 263-270.

Research output: Contribution to journalArticle

Axelsson, Alf ; Nuttall, Alfred ; Miller, Josef M. / Observations of cochlear microcirculation using intravital microscopy. In: Acta Oto-Laryngologica. 1990 ; Vol. 109, No. 3-4. pp. 263-270.
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