Obesity, Exercise, Obstructive Sleep Apnea, and Modifiable Atherosclerotic Cardiovascular Disease Risk Factors in Atrial Fibrillation

Jared Miller, Konstantinos N. Aronis, Jonathan Chrispin, Kaustubha D. Patil, Joseph E. Marine, Seth S. Martin, Michael J. Blaha, Roger S. Blumenthal, Hugh Calkins

Research output: Contribution to journalReview article

65 Scopus citations

Abstract

Classically, the 3 pillars of atrial fibrillation (AF) management have included anticoagulation for prevention of thromboembolism, rhythm control, and rate control. In both prevention and management of AF, a growing body of evidence supports an increased role for comprehensive cardiac risk factor modification (RFM), herein defined as management of traditional modifiable cardiac risk factors, weight loss, and exercise. In this narrative review, we summarize the evidence demonstrating the importance of each facet of RFM in AF prevention and therapy. Additionally, we review emerging data on the importance of weight loss and cardiovascular exercise in prevention and management of AF.

Original languageEnglish (US)
Pages (from-to)2899-2906
Number of pages8
JournalJournal of the American College of Cardiology
Volume66
Issue number25
DOIs
StatePublished - Dec 29 2015
Externally publishedYes

Keywords

  • diabetes
  • hyperlipidemia
  • hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

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    Miller, J., Aronis, K. N., Chrispin, J., Patil, K. D., Marine, J. E., Martin, S. S., Blaha, M. J., Blumenthal, R. S., & Calkins, H. (2015). Obesity, Exercise, Obstructive Sleep Apnea, and Modifiable Atherosclerotic Cardiovascular Disease Risk Factors in Atrial Fibrillation. Journal of the American College of Cardiology, 66(25), 2899-2906. https://doi.org/10.1016/j.jacc.2015.10.047