TY - JOUR
T1 - Obesity and Falls in a Prospective Study of Older Men
T2 - The Osteoporotic Fractures in Men Study
AU - Hooker, Elizabeth R.
AU - Shrestha, Smriti
AU - Lee, Christine G.
AU - Cawthon, Peggy M.
AU - Abrahamson, Melanie
AU - Ensrud, Kris
AU - Stefanick, Marcia L.
AU - Dam, Thuy Tien
AU - Marshall, Lynn M.
AU - Orwoll, Eric S.
AU - Nielson, Carrie M.
N1 - Publisher Copyright:
© The Author(s) 2016.
PY - 2017/10/1
Y1 - 2017/10/1
N2 - Objective: The aim of this study is to evaluate fall rates across body mass index (BMI) categories by age group, considering physical performance and comorbidities. Method: In the Osteoporotic Fractures in Men (MrOS) study, 5,834 men aged ≥65 reported falls every 4 months over 4.8 (±0.8) years. Adjusted associations between BMI and an incident fall were tested using mixed-effects models. Results: The fall rate (0.66/man-year overall, 95% confidence interval [CI] = [0.65, 0.67]) was lowest in the youngest, normal weight men (0.44/man-year, 95% CI = [0.41, 0.47]) and greatest in the oldest, highest BMI men (1.47 falls/man-year, 95% CI = [1.22, 1.76]). Obesity was associated with a 24% to 92% increased fall risk in men below 80 (ptrend ≤.0001, p for interaction by age =.03). Only adjustment for dynamic balance test altered the BMI-falls association substantially. Discussion: Obesity was independently associated with higher fall rates in men 65 to 80 years old. Narrow walk time, a measure of gait stability, may mediate the association.
AB - Objective: The aim of this study is to evaluate fall rates across body mass index (BMI) categories by age group, considering physical performance and comorbidities. Method: In the Osteoporotic Fractures in Men (MrOS) study, 5,834 men aged ≥65 reported falls every 4 months over 4.8 (±0.8) years. Adjusted associations between BMI and an incident fall were tested using mixed-effects models. Results: The fall rate (0.66/man-year overall, 95% confidence interval [CI] = [0.65, 0.67]) was lowest in the youngest, normal weight men (0.44/man-year, 95% CI = [0.41, 0.47]) and greatest in the oldest, highest BMI men (1.47 falls/man-year, 95% CI = [1.22, 1.76]). Obesity was associated with a 24% to 92% increased fall risk in men below 80 (ptrend ≤.0001, p for interaction by age =.03). Only adjustment for dynamic balance test altered the BMI-falls association substantially. Discussion: Obesity was independently associated with higher fall rates in men 65 to 80 years old. Narrow walk time, a measure of gait stability, may mediate the association.
KW - BMI
KW - falls
KW - obesity
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U2 - 10.1177/0898264316660412
DO - 10.1177/0898264316660412
M3 - Article
C2 - 27469600
AN - SCOPUS:85029650972
SN - 0898-2643
VL - 29
SP - 1235
EP - 1250
JO - Journal of Aging and Health
JF - Journal of Aging and Health
IS - 7
ER -