Nucleotide sequence of a cDNA encoding murine fumarylacetoacetate hydrolase

Markus Grompe, Muhsen Al-Dhalimy

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Hereditary tyrosinemia type I is caused by deficiency of the enzyme fumarylacetoacetate hydrolase (FAH) (EC 3.7.1.2), the final step in tyrosine degradation. We report here the cloning and sequencing of a full length cDNA coding for murine FAH. This cDNA is highly homologous to the previously cloned human and rat genes.

Original languageEnglish (US)
Pages (from-to)26-31
Number of pages6
JournalBiochemical Medicine and Metabolic Biology
Volume48
Issue number1
DOIs
StatePublished - Aug 1992

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry

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