TY - BOOK
T1 - Novel designs of early phase trials for cancer therapeutics
AU - Kummar, Shivaani
AU - Takimoto, Chris H.
N1 - Publisher Copyright:
© 2018 Elsevier Inc. All rights reserved.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular profiling, the changes in early phase trial designs, and endpoints to optimally develop a new generation of cancer therapeutics. The book discusses topics such as statistical perspectives on cohort expansions, the role and application of molecular profiling and how to integrate biomarkers in early phase trials. Additionally, it discusses how to incorporate patient reported outcomes in phase one trials. This book is a valuable resource for medical oncologists, basic and translational biomedical scientists, and trainees in oncology and pharmacology who are interested in learning how to improve their research by using early phase trials.
AB - Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular profiling, the changes in early phase trial designs, and endpoints to optimally develop a new generation of cancer therapeutics. The book discusses topics such as statistical perspectives on cohort expansions, the role and application of molecular profiling and how to integrate biomarkers in early phase trials. Additionally, it discusses how to incorporate patient reported outcomes in phase one trials. This book is a valuable resource for medical oncologists, basic and translational biomedical scientists, and trainees in oncology and pharmacology who are interested in learning how to improve their research by using early phase trials.
UR - http://www.scopus.com/inward/record.url?scp=85081367188&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85081367188&partnerID=8YFLogxK
U2 - 10.1016/C2016-0-03224-2
DO - 10.1016/C2016-0-03224-2
M3 - Book
AN - SCOPUS:85081367188
SN - 9780128125700
BT - Novel designs of early phase trials for cancer therapeutics
PB - Elsevier
ER -