Notes from some crypt watchers: Regulation of renewal in the mouse intestinal epithelium

Thaddeus S. Stappenbeck, Melissa Wong, Jennifer R. Saam, Indira U. Mysorekar, Jeffrey I. Gordon

Research output: Contribution to journalArticle

120 Scopus citations


The mouse intestinal epithelium undergoes rapid renewal throughout life, thereby requiring continuous coordination of its cellular proliferation, differentiation, and death programs. Recent advances in our understanding of this process have highlighted some of the molecules that regulate renewal and their potential roles in gut neoplasia.

Original languageEnglish (US)
Pages (from-to)702-709
Number of pages8
JournalCurrent Opinion in Cell Biology
Issue number6
Publication statusPublished - Dec 1998
Externally publishedYes


ASJC Scopus subject areas

  • Cell Biology

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