Normal arterial blood pressure in the nephrectomized fetal lamb

Nancy D. Binder, Debra F. Anderson, D. Mark Potter, Kent L. Thornburg, J. J. Faber

    Research output: Contribution to journalArticle

    1 Scopus citations

    Abstract

    Arterial blood pressures in 18 lambs who had been nephrectomized 3–24 days before were not significantly different from those of 26 control fetuses or from those of control fetuses in the literature. Plasma renin activities were below the detection level of our assay. The nephrectomized fetuses continued to grow according to a variety of indices. We concluded that neither the kidney nor the renin angiotensin system are necessary for the long-term regulation of fetal blood pressure, probably because of their inability to affect placental exchange of water and electrolytes.

    Original languageEnglish (US)
    Pages (from-to)50-58
    Number of pages9
    JournalNeonatology
    Volume42
    Issue number1-2
    DOIs
    StatePublished - Jan 1 1982

    Keywords

    • Fetal growth
    • Nonrenal regulation of blood pressure
    • Placental water exchange
    • Plasma renin activity

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Developmental Biology

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  • Cite this

    Binder, N. D., Anderson, D. F., Mark Potter, D., Thornburg, K. L., & Faber, J. J. (1982). Normal arterial blood pressure in the nephrectomized fetal lamb. Neonatology, 42(1-2), 50-58. https://doi.org/10.1159/000241575