Nonpharmacologic treatment of hypertriglyceridemia: Focus on fish oils

W. S. Harris

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Early studies in Greenland Eskimos stimulated interest in evaluating the effect of Omega-3 fatty acids on coronary artery disease. Subsequent studies showed a significant decrease in triglyceride levels in patients receiving high doses of fish oil containing DHA and EPA. Slight increases in LDL were also observed in patients receiving fish oil supplements. These studies have also shown a dose-response effect which persists as long as supplementation continues. Later trials, specifically the Diet and Reinfarction Trial and the Indian Experiment of Infarct Survival, have demonstrated a reduction in cardiac death rates and in the incidence of cardiac symptoms in patients receiving fish oil.

Original languageEnglish (US)
Pages (from-to)II40-II43
JournalClinical Cardiology
Issue number6 SUPPL.
StatePublished - 1999
Externally publishedYes


  • Coronary artery disease
  • DHA
  • EPA
  • Fish oil
  • High-density lipoprotein
  • Low- density lipoprotein
  • Omega-3 fatty acids
  • Triglycerides

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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