Noninvasive Topical In Vivo Imaging of Skin

Confocal Reflectance Microscopy and Polarized Light Imaging

Steven Jacques

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Topical, noninvasive, label-free imaging of skin can be accomplished using a variety of techniques. This chapter discusses two methods that are sensitive to the structure of tissue on the 10-10-μm scale because they are based on light scattering, as opposed to methods, such as fluorescence and Raman spectroscopy that inform about the chemical composition of a tissue. The two methods are: (1) confocal reflectance imaging that includes both confocal scanning laser microscopy (CSLM) and optical coherence tomography (OCT), and (2) polarized light imaging, which is sensitive to both light-scattering structures and birefringent fibers like collagen and actin-myosin.

Original languageEnglish (US)
Title of host publicationImaging in Dermatology
PublisherElsevier Inc.
Pages281-290
Number of pages10
ISBN (Print)9780128028384
DOIs
StatePublished - Aug 19 2016

Fingerprint

Confocal Microscopy
Light
Skin
Raman Spectrum Analysis
Fluorescence Spectrometry
Optical Coherence Tomography
Myosins
Actins
Collagen

Keywords

  • Confocal reflectance (CR)
  • Confocal scanning laser microscopy (CSLM)
  • Optical coherence tomography (OCT)
  • Optical scattering

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Noninvasive Topical In Vivo Imaging of Skin : Confocal Reflectance Microscopy and Polarized Light Imaging. / Jacques, Steven.

Imaging in Dermatology. Elsevier Inc., 2016. p. 281-290.

Research output: Chapter in Book/Report/Conference proceedingChapter

Jacques, Steven. / Noninvasive Topical In Vivo Imaging of Skin : Confocal Reflectance Microscopy and Polarized Light Imaging. Imaging in Dermatology. Elsevier Inc., 2016. pp. 281-290
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