Nonfamilial Adenomatous Polyposis/Nonhereditary Nonpolyposis Colorectal Cancer Hereditary Polyposis and Cancer Syndromes (MAP, Syndrome-X, Muir-Torre, etc)

Jennifer D. Rea, Daniel Herzig

Research output: Contribution to journalArticle

Abstract

Lynch syndrome and familial adenomatous polyposis represent the large majority of hereditary colorectal cancers; however, several additional less common syndromes are also associated with increased risk for developing malignancy. Identification of these syndromes requires an understanding of the phenotype to recognize the disease. Proper management of individuals and families affected by these syndromes provides an opportunity for cancer prevention. The purpose of this article is to provide a concise overview of the hereditary polyposis and colorectal cancer syndromes, exclusive of familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer.

Original languageEnglish (US)
Pages (from-to)82-87
Number of pages6
JournalSeminars in Colon and Rectal Surgery
Volume22
Issue number2
DOIs
StatePublished - Jun 2011

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Muir-Torre Syndrome
Hereditary Neoplastic Syndromes
Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms
Adenomatous Polyposis Coli
Neoplasms
Phenotype

ASJC Scopus subject areas

  • Gastroenterology
  • Surgery

Cite this

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AB - Lynch syndrome and familial adenomatous polyposis represent the large majority of hereditary colorectal cancers; however, several additional less common syndromes are also associated with increased risk for developing malignancy. Identification of these syndromes requires an understanding of the phenotype to recognize the disease. Proper management of individuals and families affected by these syndromes provides an opportunity for cancer prevention. The purpose of this article is to provide a concise overview of the hereditary polyposis and colorectal cancer syndromes, exclusive of familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer.

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