Nonerosive reflux disease - Current concepts and dilemmas

Ronnie Fass, M. Brian Fennerty, Nimish Vakil

Research output: Contribution to journalReview article

249 Scopus citations

Abstract

Nonerosive reflux disease is defined as the presence of typical symptoms of gastroesophageal reflux disease caused by intraesophageal acid in the absence of visible esophageal mucosal injury at endoscopy. Recent studies demonstrate that it is a chronic disease with a significant impact on quality of life, and it is very common in primary care settings. Treatment with acid inhibitory agents is effective, and proton pump inhibitors are the most effective form of therapy.

Original languageEnglish (US)
Pages (from-to)303-314
Number of pages12
JournalAmerican Journal of Gastroenterology
Volume96
Issue number2
DOIs
StatePublished - Mar 13 2001

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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