Non-motor Parkinsonism

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Recent years have brought increased awareness of and attention to the non-motor aspects of Parkinson's disease. Non-motor features encompass a surprisingly broad clinical spectrum that includes sensory dysfunction, behavioral abnormalities, autonomic impairment, sleep disturbances, and fatigue. Some of these features, such as impaired olfaction, REM sleep behavior disorder, and constipation, may develop long before the classic motor features of Parkinson's disease make their appearance, while others emerge in concert with disease progression. The early emergence of some non-motor features presents diagnostic opportunities, while the dopa-unresponsiveness of others poses treatment challenges, especially in the advanced stages of the disease.

Original languageEnglish (US)
JournalParkinsonism and Related Disorders
Volume13
Issue numberSUPPL. 3
DOIs
StatePublished - 2007
Externally publishedYes

Fingerprint

Parkinsonian Disorders
Parkinson Disease
REM Sleep Behavior Disorder
Dihydroxyphenylalanine
Smell
Constipation
Fatigue
Disease Progression
Sleep
Therapeutics

Keywords

  • Autonomic dysfunction
  • Behavioral abnormalities
  • Fatigue
  • Parkinson's disease
  • Sensory dysfunction
  • Sleep disturbances

ASJC Scopus subject areas

  • Aging
  • Clinical Neurology
  • Neurology

Cite this

Non-motor Parkinsonism. / Pfeiffer, Ronald.

In: Parkinsonism and Related Disorders, Vol. 13, No. SUPPL. 3, 2007.

Research output: Contribution to journalArticle

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