Nodding Syndrome in the Spotlight – Placing Recent Findings in Perspective

Peter S. Spencer; Erich Schmutzhard; Andrea S. Winkler

doi:10.1016/j.pt.2017.05.001

Nodding Syndrome in the Spotlight – Placing Recent Findings in Perspective

Peter S. Spencer, Erich Schmutzhard, Andrea S. Winkler

Neurology

Research output: Contribution to journal › Short survey › peer-review

13 Scopus citations

Abstract

Nodding syndrome (NS) is a debated scientific topic. A recently published study suggests that NS is an autoimmune disorder based on findings of cross-reacting antibodies between neuronal structures and a protein present in Onchocerca volvulus (OV). In our opinion, the proposed causal relationship between OV infection and NS has yet to be demonstrated and, instead, OV infection in NS may be opportunistic.

Original language	English (US)
Pages (from-to)	490-492
Number of pages	3
Journal	Trends in Parasitology
Volume	33
Issue number	7
DOIs	https://doi.org/10.1016/j.pt.2017.05.001
State	Published - Jul 2017

ASJC Scopus subject areas

Parasitology
Infectious Diseases

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10.1016/j.pt.2017.05.001

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title = "Nodding Syndrome in the Spotlight – Placing Recent Findings in Perspective",

abstract = "Nodding syndrome (NS) is a debated scientific topic. A recently published study suggests that NS is an autoimmune disorder based on findings of cross-reacting antibodies between neuronal structures and a protein present in Onchocerca volvulus (OV). In our opinion, the proposed causal relationship between OV infection and NS has yet to be demonstrated and, instead, OV infection in NS may be opportunistic.",

author = "Spencer, {Peter S.} and Erich Schmutzhard and Winkler, {Andrea S.}",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Ltd",

year = "2017",

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AU - Spencer, Peter S.

AU - Schmutzhard, Erich

AU - Winkler, Andrea S.

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N2 - Nodding syndrome (NS) is a debated scientific topic. A recently published study suggests that NS is an autoimmune disorder based on findings of cross-reacting antibodies between neuronal structures and a protein present in Onchocerca volvulus (OV). In our opinion, the proposed causal relationship between OV infection and NS has yet to be demonstrated and, instead, OV infection in NS may be opportunistic.

AB - Nodding syndrome (NS) is a debated scientific topic. A recently published study suggests that NS is an autoimmune disorder based on findings of cross-reacting antibodies between neuronal structures and a protein present in Onchocerca volvulus (OV). In our opinion, the proposed causal relationship between OV infection and NS has yet to be demonstrated and, instead, OV infection in NS may be opportunistic.

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M3 - Short survey

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AN - SCOPUS:85020229660

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JO - Trends in Parasitology

JF - Trends in Parasitology

IS - 7

ER -

Nodding Syndrome in the Spotlight – Placing Recent Findings in Perspective

Abstract

ASJC Scopus subject areas

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