No fits at Uffizi: Fatal forty DDI: Phenytoin, cyclosporine, CYP3A4

Michael Hutchens, Christine M. Formea

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This case discusses a pharmacokinetic interaction between cyclosporine and phenytoin, leading to organ rejection. Cyclosporin is a cytochrome P450 3A4 substrate and phenytoin is a 3A4 inducer.

Original languageEnglish (US)
Title of host publicationA Case Approach to Perioperative Drug-Drug Interactions
PublisherSpringer New York
Pages705-707
Number of pages3
ISBN (Electronic)9781461474951
ISBN (Print)9781461474944
DOIs
Publication statusPublished - Sep 15 2015

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hutchens, M., & Formea, C. M. (2015). No fits at Uffizi: Fatal forty DDI: Phenytoin, cyclosporine, CYP3A4. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 705-707). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_157