NMDA receptors turn to another channel for inhibition

N. E. Schoppa, G. L. Westbrook

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

Activation of glutamate receptors generally increases neuronal excitability. However, Isaacson and Murphy show in olfactory bulb granule cells that NMDA receptor-mediated calcium influx couples to large conductance (BK) calcium-activated potassium channels. The resulting inhibition is long lasting, which may be critical to the operation of the dynamic circuitry of the bulb.

Original languageEnglish (US)
Pages (from-to)877-879
Number of pages3
JournalNeuron
Volume31
Issue number6
DOIs
StatePublished - Sep 27 2001

ASJC Scopus subject areas

  • Neuroscience(all)

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