Nimodipine does not improve neurologic outcome after 14 minutes of cardiac arrest in cats

Akio Tateishi; Jerry E. Fleischer; John C. Drummond; Mark S. Scheller; Mark H. Zornow; Marjorie R. Grafe; Harvey M. Shapiro

doi:10.1161/01.STR.20.8.1044

Nimodipine does not improve neurologic outcome after 14 minutes of cardiac arrest in cats

Akio Tateishi, Jerry E. Fleischer, John C. Drummond, Mark S. Scheller, Mark H. Zornow, Marjorie R. Grafe, Harvey M. Shapiro

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

We tested the effects of nimodipine upon neurologic outcome in 31 cats subjected to 14 minutes of cardiac arrest followed by resuscitation. With the dose schedule used, nimodipine had no effect upon neurologic outcome or upon the percentage of ischemic neurons in frontal, hippocampal, occipital, or cerebellar brain sections. The electroencephalographic recovery pattern did not correlate with neurologic or pathologic findings.

Original language	English (US)
Pages (from-to)	1044-1050
Number of pages	7
Journal	Stroke
Volume	20
Issue number	8
DOIs	https://doi.org/10.1161/01.STR.20.8.1044
State	Published - Aug 1989
Externally published	Yes

Keywords

Cats
Heart arrest
Nimodipine

ASJC Scopus subject areas

Clinical Neurology
Cardiology and Cardiovascular Medicine
Advanced and Specialized Nursing

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10.1161/01.STR.20.8.1044

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keywords = "Cats, Heart arrest, Nimodipine",

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AU - Scheller, Mark S.

AU - Zornow, Mark H.

AU - Grafe, Marjorie R.

AU - Shapiro, Harvey M.

PY - 1989/8

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AB - We tested the effects of nimodipine upon neurologic outcome in 31 cats subjected to 14 minutes of cardiac arrest followed by resuscitation. With the dose schedule used, nimodipine had no effect upon neurologic outcome or upon the percentage of ischemic neurons in frontal, hippocampal, occipital, or cerebellar brain sections. The electroencephalographic recovery pattern did not correlate with neurologic or pathologic findings.

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KW - Heart arrest

KW - Nimodipine

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Nimodipine does not improve neurologic outcome after 14 minutes of cardiac arrest in cats

Abstract

Keywords

ASJC Scopus subject areas

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