Nimodipine does not improve neurologic outcome after 14 minutes of cardiac arrest in cats

Akio Tateishi, Jerry E. Fleischer, John C. Drummond, Mark S. Scheller, Mark H. Zornow, Marjorie R. Grafe, Harvey M. Shapiro

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

We tested the effects of nimodipine upon neurologic outcome in 31 cats subjected to 14 minutes of cardiac arrest followed by resuscitation. With the dose schedule used, nimodipine had no effect upon neurologic outcome or upon the percentage of ischemic neurons in frontal, hippocampal, occipital, or cerebellar brain sections. The electroencephalographic recovery pattern did not correlate with neurologic or pathologic findings.

Original languageEnglish (US)
Pages (from-to)1044-1050
Number of pages7
JournalStroke
Volume20
Issue number8
DOIs
StatePublished - Aug 1989

Keywords

  • Cats
  • Heart arrest
  • Nimodipine

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing

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    Tateishi, A., Fleischer, J. E., Drummond, J. C., Scheller, M. S., Zornow, M. H., Grafe, M. R., & Shapiro, H. M. (1989). Nimodipine does not improve neurologic outcome after 14 minutes of cardiac arrest in cats. Stroke, 20(8), 1044-1050. https://doi.org/10.1161/01.STR.20.8.1044