Newborn electroencephalographic correlates of maternal prenatal depressive symptoms

H. C. Gustafsson, P. G. Grieve, E. A. Werner, P. Desai, C. Monk

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Maternal perinatal depression exerts pervasive effects on the developing brain, as evidenced by electroencephalographic (EEG) patterns that differ between children of women who do and do not meet DSM or ICD diagnostic criteria. However, little research has examined if the same EEG pattern of right-frontal alpha asymmetry exists in newborns and thus originates in utero independent of postnatal influences, and if depressive symptoms are associated with this neural signature. Utilizing 125-lead EEG (n=18), this study considered clinician-rated maternal prenatal depressive symptoms in relation to newborn EEG. Maternal depressive symptomatology was associated with greater relative right-frontal alpha asymmetry during quiet sleep. These results suggest that even subclinical levels of maternal depression may influence infant brain development, and further support the role of the prenatal environment in shaping children's future neurobehavioral trajectories.

Original languageEnglish (US)
Pages (from-to)381-385
Number of pages5
JournalJournal of Developmental Origins of Health and Disease
Volume9
Issue number4
DOIs
StatePublished - Aug 1 2018

Keywords

  • electroencephalography
  • newborn
  • pregnancy
  • prenatal depression

ASJC Scopus subject areas

  • Medicine (miscellaneous)

Fingerprint

Dive into the research topics of 'Newborn electroencephalographic correlates of maternal prenatal depressive symptoms'. Together they form a unique fingerprint.

Cite this