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- Pulmonary and Respiratory Medicine
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New method for rapid and dynamic quantification of elastase activity on sputum neutrophils from patients with cystic fibrosis using flow cytometry. / Hagner, Matthias; Frey, Dario L.; Guerra, Matteo et al.In: European Respiratory Journal, Vol. 55, No. 4, 1902355, 01.04.2020.
Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - New method for rapid and dynamic quantification of elastase activity on sputum neutrophils from patients with cystic fibrosis using flow cytometry
AU - Hagner, Matthias
AU - Frey, Dario L.
AU - Guerra, Matteo
AU - Dittrich, A. Susanne
AU - Halls, Victoria S.
AU - Wege, Sabine
AU - Herth, Felix J.F.
AU - Schultz, Carsten
AU - Mall, Marcus A.
N1 - Funding Information: Support statement: Supported in part by grants from the German Ministry for Education and Research (FKZ 82DZL004A1 to M.A. Mall and C. Schultz), the German Cystic Fibrosis Association Mukoviszidose e.V. (Project number 1605 to A.S. Dittrich), the German Research Foundation (SFB-TR84TP B08 to M.A. Mall) and the Einstein Foundation Berlin (EP-2017-393 to M.A. Mall). A.S. Dittrich was supported by a HRCMM (Heidelberg Research Centre for Molecular Medicine) career development fellowship and M. Guerra is a fellow of the Molecular Medicine Partnership Unit (MMPU) between EMBL and the University Clinic Heidelberg. Funding information for this article has been deposited with the Crossref Funder Registry. Funding Information: Conflict of interest: M. Hagner has nothing to disclose. D.L. Frey has nothing to disclose. M. Guerra has nothing to disclose. A.S. Dittrich reports grants from German Cystic Fibrosis Association Mukoviszidose e. V. (grant number 1605), during the conduct of the study. V.S. Halls has nothing to disclose. S. Wege has nothing to disclose. F.J.F. Herth reports personal fees from Uptake, BTG, Olympus, Pulmonx and Roche, outside the submitted work. C. Schultz reports grants from Bundesministerium fuer Bildung und Forschung (Deutsches Zentrum fuer Lungenforschung), during the conduct of the study. M.A. Mall reports grants from German Federal Ministry of Education and Research (grant 82DZL004A1), German Research Foundation (grant SFB-TR84TP B08) and Einstein Foundation Berlin (grant EP-2017-393), during the conduct of the study; personal fees for consultancy and lectures from Bayer, personal fees for advisory board work, consultancy and lectures from Boehringer Ingelheim and Vertex Pharmaceuticals, personal fees for advisory board work and consultancy from Polyphor, Arrowhead Pharmaceuticals, ProQR Therapeutics, Spyryx Biosciences, Santhera and Enterprise Therapeutics, personal fees for consultancy from Galapagos and Sterna Biologicals, personal fees for lectures from Celtaxys, outside the submitted work; and is listed on a patent on the Scnn1b-transgenic mouse with royalties paid.
PY - 2020/4/1
Y1 - 2020/4/1
UR - http://www.scopus.com/inward/record.url?scp=85084961208&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85084961208&partnerID=8YFLogxK
U2 - 10.1183/13993003.02355-2019
DO - 10.1183/13993003.02355-2019
M3 - Article
C2 - 32139467
AN - SCOPUS:85084961208
VL - 55
JO - The European respiratory journal
JF - The European respiratory journal
SN - 0903-1936
IS - 4
M1 - 1902355