New endpoint for ablation of ventricular tachycardia

Change in QRS morphology with pacing at protected isthmus as index of isthmus block

Rupa Bala, Sandhya Dhruvakumar, Shuaib A. Latif, Francis E. Marchlinski

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

New Endpoint for Ablation of Ventricular Tachycardia. Introduction: Endpoints confirming block in the critical isthmus in sinus rhythm and with pace mapping have not been established. Methods and Results: A 44-year-old man with a history of Tetralogy of Fallot presented with recurrent ventricular tachycardia (VT). Entrainment mapping was consistent with a macroreentrant circuit rotating in a clockwise fashion under the pulmonic valve. After termination of the VT in a critical isthmus located on the conal free wall, a pace map proximal to the site of successful ablation was consistent with a change in QRS morphology. This change in QRS morphology suggested critical isthmus block and successful ablation, which was confirmed by noninducibility with programmed stimulation. Conclusion: Evidence of conduction block can be used as an additional endpoint for successful ablation of VT.

Original languageEnglish (US)
Pages (from-to)320-324
Number of pages5
JournalJournal of Cardiovascular Electrophysiology
Volume21
Issue number3
DOIs
StatePublished - 2010
Externally publishedYes

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Ventricular Tachycardia
Tetralogy of Fallot
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Keywords

  • Electroanatomical mapping
  • Tetralogy of Fallot
  • Ventricular tachycardia
  • VT ablation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)
  • Medicine(all)

Cite this

New endpoint for ablation of ventricular tachycardia : Change in QRS morphology with pacing at protected isthmus as index of isthmus block. / Bala, Rupa; Dhruvakumar, Sandhya; Latif, Shuaib A.; Marchlinski, Francis E.

In: Journal of Cardiovascular Electrophysiology, Vol. 21, No. 3, 2010, p. 320-324.

Research output: Contribution to journalArticle

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