New endpoint for ablation of ventricular tachycardia: Change in QRS morphology with pacing at protected isthmus as index of isthmus block

Rupa Bala, Sandhya Dhruvakumar, Shuaib A. Latif, Francis E. Marchlinski

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

New Endpoint for Ablation of Ventricular Tachycardia. Introduction: Endpoints confirming block in the critical isthmus in sinus rhythm and with pace mapping have not been established. Methods and Results: A 44-year-old man with a history of Tetralogy of Fallot presented with recurrent ventricular tachycardia (VT). Entrainment mapping was consistent with a macroreentrant circuit rotating in a clockwise fashion under the pulmonic valve. After termination of the VT in a critical isthmus located on the conal free wall, a pace map proximal to the site of successful ablation was consistent with a change in QRS morphology. This change in QRS morphology suggested critical isthmus block and successful ablation, which was confirmed by noninducibility with programmed stimulation. Conclusion: Evidence of conduction block can be used as an additional endpoint for successful ablation of VT.

Original languageEnglish (US)
Pages (from-to)320-324
Number of pages5
JournalJournal of cardiovascular electrophysiology
Volume21
Issue number3
DOIs
StatePublished - Mar 2010

Keywords

  • Electroanatomical mapping
  • Tetralogy of Fallot
  • VT ablation
  • Ventricular tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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