New endpoint for ablation of ventricular tachycardia: Change in QRS morphology with pacing at protected isthmus as index of isthmus block

Rupa Bala, Sandhya Dhruvakumar, Shuaib A. Latif, Francis E. Marchlinski

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

New Endpoint for Ablation of Ventricular Tachycardia. Introduction: Endpoints confirming block in the critical isthmus in sinus rhythm and with pace mapping have not been established. Methods and Results: A 44-year-old man with a history of Tetralogy of Fallot presented with recurrent ventricular tachycardia (VT). Entrainment mapping was consistent with a macroreentrant circuit rotating in a clockwise fashion under the pulmonic valve. After termination of the VT in a critical isthmus located on the conal free wall, a pace map proximal to the site of successful ablation was consistent with a change in QRS morphology. This change in QRS morphology suggested critical isthmus block and successful ablation, which was confirmed by noninducibility with programmed stimulation. Conclusion: Evidence of conduction block can be used as an additional endpoint for successful ablation of VT.

Original languageEnglish (US)
Pages (from-to)320-324
Number of pages5
JournalJournal of Cardiovascular Electrophysiology
Volume21
Issue number3
DOIs
StatePublished - 2010
Externally publishedYes

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Ventricular Tachycardia
Tetralogy of Fallot
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Keywords

  • Electroanatomical mapping
  • Tetralogy of Fallot
  • Ventricular tachycardia
  • VT ablation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)
  • Medicine(all)

Cite this

New endpoint for ablation of ventricular tachycardia : Change in QRS morphology with pacing at protected isthmus as index of isthmus block. / Bala, Rupa; Dhruvakumar, Sandhya; Latif, Shuaib A.; Marchlinski, Francis E.

In: Journal of Cardiovascular Electrophysiology, Vol. 21, No. 3, 2010, p. 320-324.

Research output: Contribution to journalArticle

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