TY - JOUR
T1 - New endpoint for ablation of ventricular tachycardia
T2 - Change in QRS morphology with pacing at protected isthmus as index of isthmus block
AU - Bala, Rupa
AU - Dhruvakumar, Sandhya
AU - Latif, Shuaib A.
AU - Marchlinski, Francis E.
PY - 2010/3
Y1 - 2010/3
N2 - New Endpoint for Ablation of Ventricular Tachycardia. Introduction: Endpoints confirming block in the critical isthmus in sinus rhythm and with pace mapping have not been established. Methods and Results: A 44-year-old man with a history of Tetralogy of Fallot presented with recurrent ventricular tachycardia (VT). Entrainment mapping was consistent with a macroreentrant circuit rotating in a clockwise fashion under the pulmonic valve. After termination of the VT in a critical isthmus located on the conal free wall, a pace map proximal to the site of successful ablation was consistent with a change in QRS morphology. This change in QRS morphology suggested critical isthmus block and successful ablation, which was confirmed by noninducibility with programmed stimulation. Conclusion: Evidence of conduction block can be used as an additional endpoint for successful ablation of VT.
AB - New Endpoint for Ablation of Ventricular Tachycardia. Introduction: Endpoints confirming block in the critical isthmus in sinus rhythm and with pace mapping have not been established. Methods and Results: A 44-year-old man with a history of Tetralogy of Fallot presented with recurrent ventricular tachycardia (VT). Entrainment mapping was consistent with a macroreentrant circuit rotating in a clockwise fashion under the pulmonic valve. After termination of the VT in a critical isthmus located on the conal free wall, a pace map proximal to the site of successful ablation was consistent with a change in QRS morphology. This change in QRS morphology suggested critical isthmus block and successful ablation, which was confirmed by noninducibility with programmed stimulation. Conclusion: Evidence of conduction block can be used as an additional endpoint for successful ablation of VT.
KW - Electroanatomical mapping
KW - Tetralogy of Fallot
KW - VT ablation
KW - Ventricular tachycardia
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U2 - 10.1111/j.1540-8167.2009.01596.x
DO - 10.1111/j.1540-8167.2009.01596.x
M3 - Article
C2 - 19732230
AN - SCOPUS:77649130255
SN - 1045-3873
VL - 21
SP - 320
EP - 324
JO - Journal of cardiovascular electrophysiology
JF - Journal of cardiovascular electrophysiology
IS - 3
ER -