New advances in fetal cardiovascular magnetic resonance imaging for quantifying the distribution of blood flow and oxygen transport: Potential applications in fetal cardiovascular disease diagnosis and therapy

Liqun Sun, Christopher K. Macgowan, Sharon Portnoy, John G. Sled, Shi Joon Yoo, Lars Grosse-Wortmann, Edgar Jaeggi, John Kingdom, Mike Seed

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

Until recently, our modern understanding of fetal circulatory physiology has been largely based on invasive measurements made in fetal sheep. However, new MRI technology developed by our group has provided equivalent information about the distribution of blood flow and oxygen transport noninvasively. The initial findings largely confirm prior estimates about the human fetal circulation extrapolated from fetal sheep data and human ultrasound data. Here we describe the hemodynamics of the normal late gestation human fetal circulation by MRI and speculate about what the advent of this technology might mean in terms of the management of fetuses affected by placental insufficiency and congenital heart disease.

Original languageEnglish (US)
Pages (from-to)1799-1803
Number of pages5
JournalEchocardiography
Volume34
Issue number12
DOIs
StatePublished - Dec 2017
Externally publishedYes

Keywords

  • cardiac imaging
  • cardiac magnetic resonance imaging
  • fetal echocardiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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