Neutropenic Enterocolitis

Research output: Contribution to journalReview article

18 Scopus citations

Abstract

Neutropenic enterocolitis, also known as typhlitis or ileocecal syndrome, is a rare but important complication of neutropenia associated with malignancy. It occurs as a result of chemotherapeutic damage to the intestinal mucosa in the context of an absolute neutropenia, and can rapidly progress to intestinal perforation, multisystem organ failure, and sepsis. Presenting signs and symptoms may include fever, abdominal pain, nausea, vomiting, and diarrhea. Rapid identification by emergency physicians and timely, aggressive medical and/or surgical intervention are the cornerstones of survival for these patients.

Original languageEnglish (US)
Pages (from-to)415-422
Number of pages8
JournalEmergency Medicine Clinics of North America
Volume27
Issue number3
DOIs
StatePublished - Aug 2009

Keywords

  • Cancer
  • Chemotherapy
  • Enterocolitis
  • Fever
  • Neutropenia
  • Typhlitis

ASJC Scopus subject areas

  • Emergency Medicine

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