Neutropenic enterocolitis

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Neutropenic enterocolitis, also known as typhlitis or ileocecal syndrome, is a rare, but important, complication of neutropenia associated with malignancy. It occurs as a result of chemotherapeutic damage to the intestinal mucosa in the context of an absolute neutropenia and can rapidly progress to intestinal perforation, multisystem organ failure, and sepsis. Presenting signs and symptoms may include fever, abdominal pain, nausea, vomiting, and diarrhea. Rapid identification and timely, aggressive medical and/or surgical intervention are the cornerstones of survival for these patients.

Original languageEnglish (US)
Pages (from-to)577-584
Number of pages8
JournalHematology/Oncology Clinics of North America
Volume24
Issue number3
DOIs
StatePublished - Jun 2010

Fingerprint

Neutropenic Enterocolitis
Neutropenia
Typhlitis
Intestinal Perforation
Intestinal Mucosa
Nausea
Abdominal Pain
Signs and Symptoms
Vomiting
Diarrhea
Sepsis
Fever
Survival
Neoplasms

Keywords

  • Cancer
  • Chemotherapy
  • Enterocolitis
  • Fever
  • Neutropenia
  • Typhlitis

ASJC Scopus subject areas

  • Oncology
  • Hematology

Cite this

Neutropenic enterocolitis. / Cloutier, Robert.

In: Hematology/Oncology Clinics of North America, Vol. 24, No. 3, 06.2010, p. 577-584.

Research output: Contribution to journalArticle

@article{2c4394b5f11b4cad96c53892fdeec5e2,
title = "Neutropenic enterocolitis",
abstract = "Neutropenic enterocolitis, also known as typhlitis or ileocecal syndrome, is a rare, but important, complication of neutropenia associated with malignancy. It occurs as a result of chemotherapeutic damage to the intestinal mucosa in the context of an absolute neutropenia and can rapidly progress to intestinal perforation, multisystem organ failure, and sepsis. Presenting signs and symptoms may include fever, abdominal pain, nausea, vomiting, and diarrhea. Rapid identification and timely, aggressive medical and/or surgical intervention are the cornerstones of survival for these patients.",
keywords = "Cancer, Chemotherapy, Enterocolitis, Fever, Neutropenia, Typhlitis",
author = "Robert Cloutier",
year = "2010",
month = "6",
doi = "10.1016/j.hoc.2010.03.005",
language = "English (US)",
volume = "24",
pages = "577--584",
journal = "Hematology/Oncology Clinics of North America",
issn = "0889-8588",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - Neutropenic enterocolitis

AU - Cloutier, Robert

PY - 2010/6

Y1 - 2010/6

N2 - Neutropenic enterocolitis, also known as typhlitis or ileocecal syndrome, is a rare, but important, complication of neutropenia associated with malignancy. It occurs as a result of chemotherapeutic damage to the intestinal mucosa in the context of an absolute neutropenia and can rapidly progress to intestinal perforation, multisystem organ failure, and sepsis. Presenting signs and symptoms may include fever, abdominal pain, nausea, vomiting, and diarrhea. Rapid identification and timely, aggressive medical and/or surgical intervention are the cornerstones of survival for these patients.

AB - Neutropenic enterocolitis, also known as typhlitis or ileocecal syndrome, is a rare, but important, complication of neutropenia associated with malignancy. It occurs as a result of chemotherapeutic damage to the intestinal mucosa in the context of an absolute neutropenia and can rapidly progress to intestinal perforation, multisystem organ failure, and sepsis. Presenting signs and symptoms may include fever, abdominal pain, nausea, vomiting, and diarrhea. Rapid identification and timely, aggressive medical and/or surgical intervention are the cornerstones of survival for these patients.

KW - Cancer

KW - Chemotherapy

KW - Enterocolitis

KW - Fever

KW - Neutropenia

KW - Typhlitis

UR - http://www.scopus.com/inward/record.url?scp=77952901901&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77952901901&partnerID=8YFLogxK

U2 - 10.1016/j.hoc.2010.03.005

DO - 10.1016/j.hoc.2010.03.005

M3 - Article

C2 - 20488355

AN - SCOPUS:77952901901

VL - 24

SP - 577

EP - 584

JO - Hematology/Oncology Clinics of North America

JF - Hematology/Oncology Clinics of North America

SN - 0889-8588

IS - 3

ER -