Abstract
Glutamate is the main excitatory neurotransmitter in the brain. For many years it has been considered to act only on ligand-gated receptor channels - termed NMDA, AMPA and kainate receptors - involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate ion channels and enzymes producing second messengers via specific receptors coupled to G-proteins. The existence of these receptors, called metabotropic glutamate receptors, is changing our views on the functioning of fast excitatory synapses.
Original language | English (US) |
---|---|
Pages (from-to) | 1-26 |
Number of pages | 26 |
Journal | Neuropharmacology |
Volume | 34 |
Issue number | 1 |
DOIs | |
State | Published - 1995 |
Externally published | Yes |
ASJC Scopus subject areas
- Pharmacology
- Cellular and Molecular Neuroscience