Neuropsychiatric problems in mixed connective tissue disease

Robert (Rob) Bennett, David M. Bong, Benjamin H. Spargo

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

A group of 20 patients with mixed connective tissue disease, followed for up to five years, was found to have a 55 per cent incidence of neuropsychiatric problems. An aseptic meningitis-like syndrome was the most common presentation and was rapidly responsive to corticosteroid therapy. Other findings were psychosis, convulsions, peripheral neuropathy, trigeminal neuropathy and cerebellar ataxia. An abnormal cerebrospinal fluid was found in five patients; mild pleocytosis, an increased protein content and a first phase colloidal gold curve were the main abnormalities. These neuropsychiatric problems have not been a cause of mortality in this group of patients with mixed connective tissue disease.

Original languageEnglish (US)
Pages (from-to)955-962
Number of pages8
JournalThe American journal of medicine
Volume65
Issue number6
DOIs
StatePublished - 1978
Externally publishedYes

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Mixed Connective Tissue Disease
Trigeminal Nerve Diseases
Aseptic Meningitis
Gold Colloid
Cerebellar Ataxia
Leukocytosis
Peripheral Nervous System Diseases
Psychotic Disorders
Cerebrospinal Fluid
Adrenal Cortex Hormones
Seizures
Mortality
Incidence
Proteins
Therapeutics

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Neuropsychiatric problems in mixed connective tissue disease. / Bennett, Robert (Rob); Bong, David M.; Spargo, Benjamin H.

In: The American journal of medicine, Vol. 65, No. 6, 1978, p. 955-962.

Research output: Contribution to journalArticle

Bennett, Robert (Rob) ; Bong, David M. ; Spargo, Benjamin H. / Neuropsychiatric problems in mixed connective tissue disease. In: The American journal of medicine. 1978 ; Vol. 65, No. 6. pp. 955-962.
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