Neuronal death or dismemberment mediated by Sox14

Jeannette M. Osterloh, Marc R. Freeman

Research output: Contribution to journalShort surveypeer-review

8 Scopus citations


The pruning of unneeded axons and dendrites is crucial for circuitry maturation, but poorly understood on the molecular level. During Drosophila metamorphosis, the transcription factor Sox14 acts as a context-dependent mediator of death, axonal or dendritic pruning. Its transcriptional target Mical acts specifically in dendrite pruning.

Original languageEnglish (US)
Pages (from-to)1479-1480
Number of pages2
JournalNature Neuroscience
Issue number12
StatePublished - Dec 2009
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)


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