Neuronal death or dismemberment mediated by Sox14

Jeannette M. Osterloh, Marc R. Freeman

Research output: Contribution to journalShort surveypeer-review

9 Scopus citations

Abstract

The pruning of unneeded axons and dendrites is crucial for circuitry maturation, but poorly understood on the molecular level. During Drosophila metamorphosis, the transcription factor Sox14 acts as a context-dependent mediator of death, axonal or dendritic pruning. Its transcriptional target Mical acts specifically in dendrite pruning.

Original languageEnglish (US)
Pages (from-to)1479-1480
Number of pages2
JournalNature Neuroscience
Volume12
Issue number12
DOIs
StatePublished - Dec 2009
Externally publishedYes

ASJC Scopus subject areas

  • General Neuroscience

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