Neuronal death or dismemberment mediated by Sox14

Jeannette M. Osterloh; Marc R. Freeman

doi:10.1038/nn1209-1479

Neuronal death or dismemberment mediated by Sox14

Jeannette M. Osterloh, Marc R. Freeman

Research output: Contribution to journal › Short survey › peer-review

8 Scopus citations

Abstract

The pruning of unneeded axons and dendrites is crucial for circuitry maturation, but poorly understood on the molecular level. During Drosophila metamorphosis, the transcription factor Sox14 acts as a context-dependent mediator of death, axonal or dendritic pruning. Its transcriptional target Mical acts specifically in dendrite pruning.

Original language	English (US)
Pages (from-to)	1479-1480
Number of pages	2
Journal	Nature Neuroscience
Volume	12
Issue number	12
DOIs	https://doi.org/10.1038/nn1209-1479
State	Published - Dec 2009
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

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10.1038/nn1209-1479

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title = "Neuronal death or dismemberment mediated by Sox14",

abstract = "The pruning of unneeded axons and dendrites is crucial for circuitry maturation, but poorly understood on the molecular level. During Drosophila metamorphosis, the transcription factor Sox14 acts as a context-dependent mediator of death, axonal or dendritic pruning. Its transcriptional target Mical acts specifically in dendrite pruning.",

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AB - The pruning of unneeded axons and dendrites is crucial for circuitry maturation, but poorly understood on the molecular level. During Drosophila metamorphosis, the transcription factor Sox14 acts as a context-dependent mediator of death, axonal or dendritic pruning. Its transcriptional target Mical acts specifically in dendrite pruning.

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Neuronal death or dismemberment mediated by Sox14

Abstract

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