Neuronal death or dismemberment mediated by Sox14

Jeannette M. Osterloh, Marc R. Freeman

Research output: Contribution to journalShort survey

8 Scopus citations

Abstract

The pruning of unneeded axons and dendrites is crucial for circuitry maturation, but poorly understood on the molecular level. During Drosophila metamorphosis, the transcription factor Sox14 acts as a context-dependent mediator of death, axonal or dendritic pruning. Its transcriptional target Mical acts specifically in dendrite pruning.

Original languageEnglish (US)
Pages (from-to)1479-1480
Number of pages2
JournalNature Neuroscience
Volume12
Issue number12
DOIs
StatePublished - Dec 1 2009

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ASJC Scopus subject areas

  • Neuroscience(all)

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