Abstract
Pyridostigmine bromide (PB) promotes and then silences cholinergic muscle activity, and disrupts the junctional regions of muscle fibers and associated nerve terminals, in organotypic mouse spinal cord-muscle cultures continuously treated with low concentrations of the drug for up to 14 days. Spontaneous muscle activity is restored within 1 week of drug removal.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 305-308 |
| Number of pages | 4 |
| Journal | Journal of Physiology Paris |
| Volume | 92 |
| Issue number | 3-4 |
| DOIs | |
| State | Published - Jun 1998 |
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ASJC Scopus subject areas
- Neuroscience(all)
- Physiology (medical)
Cite this
Neuromuscular responses to pyridostigmine bromide in organotypic spinal cord-muscle culture. / Drake-Baumann, Rosemarie; Seil, Fredrick J.; Spencer, Peter.
In: Journal of Physiology Paris, Vol. 92, No. 3-4, 06.1998, p. 305-308.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Neuromuscular responses to pyridostigmine bromide in organotypic spinal cord-muscle culture
AU - Drake-Baumann, Rosemarie
AU - Seil, Fredrick J.
AU - Spencer, Peter
PY - 1998/6
Y1 - 1998/6
N2 - Pyridostigmine bromide (PB) promotes and then silences cholinergic muscle activity, and disrupts the junctional regions of muscle fibers and associated nerve terminals, in organotypic mouse spinal cord-muscle cultures continuously treated with low concentrations of the drug for up to 14 days. Spontaneous muscle activity is restored within 1 week of drug removal.
AB - Pyridostigmine bromide (PB) promotes and then silences cholinergic muscle activity, and disrupts the junctional regions of muscle fibers and associated nerve terminals, in organotypic mouse spinal cord-muscle cultures continuously treated with low concentrations of the drug for up to 14 days. Spontaneous muscle activity is restored within 1 week of drug removal.
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UR - http://www.scopus.com/inward/citedby.url?scp=0032105346&partnerID=8YFLogxK
U2 - 10.1016/S0928-4257(98)80038-7
DO - 10.1016/S0928-4257(98)80038-7
M3 - Article
C2 - 9789828
AN - SCOPUS:0032105346
VL - 92
SP - 305
EP - 308
JO - Journal de Physiologie
JF - Journal de Physiologie
SN - 0928-4257
IS - 3-4
ER -