Neuromuscular responses to pyridostigmine bromide in organotypic spinal cord-muscle culture

Rosemarie Drake-Baumann; Fredrick J. Seil; Peter S. Spencer

doi:10.1016/S0928-4257(98)80038-7

Neuromuscular responses to pyridostigmine bromide in organotypic spinal cord-muscle culture

Rosemarie Drake-Baumann, Fredrick J. Seil, Peter S. Spencer

Neurology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Pyridostigmine bromide (PB) promotes and then silences cholinergic muscle activity, and disrupts the junctional regions of muscle fibers and associated nerve terminals, in organotypic mouse spinal cord-muscle cultures continuously treated with low concentrations of the drug for up to 14 days. Spontaneous muscle activity is restored within 1 week of drug removal.

Original language	English (US)
Pages (from-to)	305-308
Number of pages	4
Journal	Journal of Physiology Paris
Volume	92
Issue number	3-4
DOIs	https://doi.org/10.1016/S0928-4257(98)80038-7
State	Published - 1998

ASJC Scopus subject areas

Neuroscience(all)
Physiology (medical)

Access to Document

10.1016/S0928-4257(98)80038-7

Cite this

@article{dcc9a067446146829827823f4d51b4bc,

title = "Neuromuscular responses to pyridostigmine bromide in organotypic spinal cord-muscle culture",

abstract = "Pyridostigmine bromide (PB) promotes and then silences cholinergic muscle activity, and disrupts the junctional regions of muscle fibers and associated nerve terminals, in organotypic mouse spinal cord-muscle cultures continuously treated with low concentrations of the drug for up to 14 days. Spontaneous muscle activity is restored within 1 week of drug removal.",

author = "Rosemarie Drake-Baumann and Seil, {Fredrick J.} and Spencer, {Peter S.}",

note = "Funding Information: Supported by a grant from the U.S. Department of Veterans",

year = "1998",

doi = "10.1016/S0928-4257(98)80038-7",

language = "English (US)",

volume = "92",

pages = "305--308",

journal = "Journal de Physiologie",

issn = "0928-4257",

publisher = "Elsevier Masson SAS",

number = "3-4",

}

TY - JOUR

T1 - Neuromuscular responses to pyridostigmine bromide in organotypic spinal cord-muscle culture

AU - Drake-Baumann, Rosemarie

AU - Seil, Fredrick J.

AU - Spencer, Peter S.

N1 - Funding Information: Supported by a grant from the U.S. Department of Veterans

PY - 1998

Y1 - 1998

N2 - Pyridostigmine bromide (PB) promotes and then silences cholinergic muscle activity, and disrupts the junctional regions of muscle fibers and associated nerve terminals, in organotypic mouse spinal cord-muscle cultures continuously treated with low concentrations of the drug for up to 14 days. Spontaneous muscle activity is restored within 1 week of drug removal.

AB - Pyridostigmine bromide (PB) promotes and then silences cholinergic muscle activity, and disrupts the junctional regions of muscle fibers and associated nerve terminals, in organotypic mouse spinal cord-muscle cultures continuously treated with low concentrations of the drug for up to 14 days. Spontaneous muscle activity is restored within 1 week of drug removal.

UR - http://www.scopus.com/inward/record.url?scp=0032105346&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032105346&partnerID=8YFLogxK

U2 - 10.1016/S0928-4257(98)80038-7

DO - 10.1016/S0928-4257(98)80038-7

M3 - Article

C2 - 9789828

AN - SCOPUS:0032105346

VL - 92

SP - 305

EP - 308

JO - Journal de Physiologie

JF - Journal de Physiologie

SN - 0928-4257

IS - 3-4

ER -

Neuromuscular responses to pyridostigmine bromide in organotypic spinal cord-muscle culture

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this