Neurological concomitants of uveitis

Aim: To describe the prevalence and types of neurological disease that occur in association with uveitis. Methods: Retrospective review of medical records of patients attending a tertiary referral uveitis service over a 15 year period. Results: Of 1450 patients with uveitis, 115 (7.9%) had neurological disease that was considered to be causally related to the eye inflammation. The most frequent neurological associations were Vogt-Koyanagi-Harada disease, primary central nervous system lymphoma, multiple sclerosis, and herpes virus infections. Conclusions: Neurological disease is common among patients attending a uveitis service. The distinctive characteristics of the uveal inflammation may be useful in diagnosing the neurological disease.