Neurofibromatosis-1 and Rhabdomyosarcoma: An Unusual Recurrence

Nadia V. Halstead, Nicholas G. Cost, Sarah L. Hecht, Jonathan P. Walker

Research output: Contribution to journalArticlepeer-review

Abstract

Neurofibromatosis-1 has a known increased risk of malignancy with rhabdomyosarcoma occurring in up to 6% of patients. Here we report on an 8-year-old male with a history of Neurofibromatosis-1 and previously treated stage 3, group III bladder/prostate embryonal rhabdomyosarcoma (diagnosed at 18 months old) who presented with penile swelling concerning for priapism. Imaging and subsequent biopsy confirmed embryonal rhabdomyosarcoma of the penile corporal bodies. Penile rhabdomyosarcoma is exceedingly rare, with less than 15 case reports in the literature. Our patient received chemoradiation per D9803 with organ preserving local control and is doing well 3 months after treatment.

Original languageEnglish (US)
Pages (from-to)168-172
Number of pages5
JournalUrology
Volume137
DOIs
StatePublished - Mar 2020
Externally publishedYes

ASJC Scopus subject areas

  • Urology

Fingerprint Dive into the research topics of 'Neurofibromatosis-1 and Rhabdomyosarcoma: An Unusual Recurrence'. Together they form a unique fingerprint.

Cite this