TY - JOUR
T1 - Neuroendocrine effects of haloperidol in an adolescent with gilles de la tourette’s disease and delayed onset of puberty
AU - Caine, Eric D.
AU - Mendelson, Wallace B.
AU - Lynn Loriaux, D.
PY - 1979/8
Y1 - 1979/8
N2 - The effects of haloperidol on the release of prolactin, growth hormone, and luteinizing hormone during sleep were studied in an adolescent male who had Gilles de la Tourette’s disease and delayed onset of puberty. At doses of 5 and 2 mg, haloperidol led to an increase of prolactin secretion and a suppression of luteinizing hormone release. Growth hormone was unaffected. Despite these changes, the patient had normal secondary sexual development consistent with puberty.
AB - The effects of haloperidol on the release of prolactin, growth hormone, and luteinizing hormone during sleep were studied in an adolescent male who had Gilles de la Tourette’s disease and delayed onset of puberty. At doses of 5 and 2 mg, haloperidol led to an increase of prolactin secretion and a suppression of luteinizing hormone release. Growth hormone was unaffected. Despite these changes, the patient had normal secondary sexual development consistent with puberty.
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U2 - 10.1097/00005053-197908000-00011
DO - 10.1097/00005053-197908000-00011
M3 - Article
C2 - 288847
AN - SCOPUS:0018366708
SN - 0022-3018
VL - 167
SP - 504
EP - 507
JO - Journal of Nervous and Mental Disease
JF - Journal of Nervous and Mental Disease
IS - 8
ER -