Neuroendocrine effects of haloperidol in an adolescent with gilles de la tourette’s disease and delayed onset of puberty

Eric D. Caine, Wallace B. Mendelson, D. Lynn Loriaux

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

The effects of haloperidol on the release of prolactin, growth hormone, and luteinizing hormone during sleep were studied in an adolescent male who had Gilles de la Tourette’s disease and delayed onset of puberty. At doses of 5 and 2 mg, haloperidol led to an increase of prolactin secretion and a suppression of luteinizing hormone release. Growth hormone was unaffected. Despite these changes, the patient had normal secondary sexual development consistent with puberty.

Original languageEnglish (US)
Pages (from-to)504-507
Number of pages4
JournalJournal of Nervous and Mental Disease
Volume167
Issue number8
DOIs
StatePublished - Aug 1979

ASJC Scopus subject areas

  • Psychiatry and Mental health

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