Neural-specific carbohydrate moiety shared by many surface glycoproteins in Drosophila and grasshopper embryos

P. M. Snow, N. H. Patel, A. L. Harrelson, C. S. Goodman

    Research output: Contribution to journalArticle

    123 Scopus citations


    Antiserum against horseradish peroxidase (anti-HRP Ab) labels the surfaces of neurons in both Drosophila and grasshopper (Jan and Jan, 1982). Here we show that the anti-HRP Ab (1) immunoprecipitates at least 17 different membrane glycoproteins from the Drosophila embryo CNS (and a similar array from grasshopper) and (2) recognizes a neural-specific carbohydrate moiety expressed by most if not all of these proteins. Although the anti-HRP Ab stains all axon pathways, 2 of the anti-HRP glycoproteins, fasciclin I and II, are expressed on specific subsets of axon pathways in the grasshopper embryo (Bastiani et al., 1987).

    Original languageEnglish (US)
    Pages (from-to)4137-4144
    Number of pages8
    JournalJournal of Neuroscience
    Issue number12
    StatePublished - Dec 1 1987


    ASJC Scopus subject areas

    • Neuroscience(all)

    Cite this