Neural-specific carbohydrate moiety shared by many surface glycoproteins in Drosophila and grasshopper embryos

P. M. Snow, N. H. Patel, Allan Harrelson, C. S. Goodman

Research output: Contribution to journalArticle

122 Citations (Scopus)

Abstract

Antiserum against horseradish peroxidase (anti-HRP Ab) labels the surfaces of neurons in both Drosophila and grasshopper (Jan and Jan, 1982). Here we show that the anti-HRP Ab (1) immunoprecipitates at least 17 different membrane glycoproteins from the Drosophila embryo CNS (and a similar array from grasshopper) and (2) recognizes a neural-specific carbohydrate moiety expressed by most if not all of these proteins. Although the anti-HRP Ab stains all axon pathways, 2 of the anti-HRP glycoproteins, fasciclin I and II, are expressed on specific subsets of axon pathways in the grasshopper embryo (Bastiani et al., 1987).

Original languageEnglish (US)
Pages (from-to)4137-4144
Number of pages8
JournalJournal of Neuroscience
Volume7
Issue number12
StatePublished - 1987
Externally publishedYes

Fingerprint

Grasshoppers
Membrane Glycoproteins
Drosophila
Embryonic Structures
Carbohydrates
Axons
Horseradish Peroxidase
Immune Sera
Glycoproteins
Neurons
Proteins

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Neural-specific carbohydrate moiety shared by many surface glycoproteins in Drosophila and grasshopper embryos. / Snow, P. M.; Patel, N. H.; Harrelson, Allan; Goodman, C. S.

In: Journal of Neuroscience, Vol. 7, No. 12, 1987, p. 4137-4144.

Research output: Contribution to journalArticle

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