Neural activation during response inhibition is associated with adolescents' frequency of risky sex and substance use

Sarah Feldstein Ewing, Jon M. Houck, Angela D. Bryan

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Objective: Introduction: While many have identified the important role of the developing brain in youth risk behavior, few have examined the relationship between salient cognitive factors (response inhibition) and different types of real-world adolescent health risk behaviors such as substance use and risky sex, within the same sample of youth. Methods: We therefore sought to examine these relationships with 95 high-risk youth (ages 14-18; M age. =. 16.29. years). We examined blood oxygen level dependent (BOLD) response to an fMRI-based cognitive task designed to assess response inhibition (Go/NoGo) and past month risk behavior (number of substance use days; number of unprotected sex days). Results: For this sample of youth, we found significant negative correlations between past month substance use and response inhibition within the left inferior frontal gyrus (IFG) and right insula (uncorrected p.

Original languageEnglish (US)
Pages (from-to)80-87
Number of pages8
JournalAddictive Behaviors
Volume44
DOIs
StatePublished - May 1 2015
Externally publishedYes

Fingerprint

Risk-Taking
Chemical activation
Health risks
Unsafe Sex
Brain
Blood
Prefrontal Cortex
Oxygen
Magnetic Resonance Imaging
Inhibition (Psychology)

Keywords

  • Adolescent
  • Alcohol
  • Cannabis
  • Cognitive
  • FMRI
  • Sexual intercourse

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology
  • Toxicology
  • Medicine (miscellaneous)

Cite this

Neural activation during response inhibition is associated with adolescents' frequency of risky sex and substance use. / Feldstein Ewing, Sarah; Houck, Jon M.; Bryan, Angela D.

In: Addictive Behaviors, Vol. 44, 01.05.2015, p. 80-87.

Research output: Contribution to journalArticle

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