Network-Module-Based Approaches in Cancer Data Analysis

Guanming Wu, Lincoln Stein

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Researchers have recognized that biological phenotypes are underlain by the network of interactions among proteins, RNAs, DNAs, and other entities in the cell. Network-based data analysis approaches have been widely used in cancer data analysis. In this chapter, we review network-module-based approaches and their applications to cancer data analysis. We also introduce a software tool for doing network-module-based data analysis for cancer data.

Original languageEnglish (US)
Title of host publicationStatistical Diagnostics for Cancer
Subtitle of host publicationAnalyzing High-Dimensional Data
PublisherWiley-VCH
Pages173-192
Number of pages20
Volume3
ISBN (Print)9783527332625
DOIs
StatePublished - Apr 8 2013
Externally publishedYes

Keywords

  • Biological pathways
  • Cytoscape plug-in
  • Functional interactions
  • Modules
  • Networks
  • Ovarian cancer
  • Reactome database

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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