Nephrotoxicity of immunosuppressive drugs

W. M. Bennett; E. Burdmann; T. Andoh; L. Elzinga; N. Franceschini

Nephrotoxicity of immunosuppressive drugs

W. M. Bennett, E. Burdmann, T. Andoh, L. Elzinga, N. Franceschini

Surgery

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18 Scopus citations

Abstract

Drugs used to modify the immune response in solid organ transplantation or autoimmune disease may cause dose-related nephrotoxicity. Cyclosporine, FK506, cyclosporine G, and rapamycin have all been studied experimentally and to a more limited extent in patients. This paper summarizes this literature using data from clinically relevant animal models.

Original language	English (US)
Pages (from-to)	214-220
Number of pages	7
Journal	Mineral and Electrolyte Metabolism
Volume	20
Issue number	4
State	Published - 1994

Keywords

Cyclosporine
FK506
Nephrotoxicity
Rapamycin

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Biochemistry

Cite this

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title = "Nephrotoxicity of immunosuppressive drugs",

abstract = "Drugs used to modify the immune response in solid organ transplantation or autoimmune disease may cause dose-related nephrotoxicity. Cyclosporine, FK506, cyclosporine G, and rapamycin have all been studied experimentally and to a more limited extent in patients. This paper summarizes this literature using data from clinically relevant animal models.",

keywords = "Cyclosporine, FK506, Nephrotoxicity, Rapamycin",

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T1 - Nephrotoxicity of immunosuppressive drugs

AU - Bennett, W. M.

AU - Burdmann, E.

AU - Andoh, T.

AU - Elzinga, L.

AU - Franceschini, N.

PY - 1994

Y1 - 1994

N2 - Drugs used to modify the immune response in solid organ transplantation or autoimmune disease may cause dose-related nephrotoxicity. Cyclosporine, FK506, cyclosporine G, and rapamycin have all been studied experimentally and to a more limited extent in patients. This paper summarizes this literature using data from clinically relevant animal models.

AB - Drugs used to modify the immune response in solid organ transplantation or autoimmune disease may cause dose-related nephrotoxicity. Cyclosporine, FK506, cyclosporine G, and rapamycin have all been studied experimentally and to a more limited extent in patients. This paper summarizes this literature using data from clinically relevant animal models.

KW - Cyclosporine

KW - FK506

KW - Nephrotoxicity

KW - Rapamycin

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M3 - Article

C2 - 7531274

AN - SCOPUS:0027962420

SN - 0378-0392

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JF - Mineral and Electrolyte Metabolism

IS - 4

ER -

Nephrotoxicity of immunosuppressive drugs

Abstract

Keywords

ASJC Scopus subject areas

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