Neoplastic seeding of squamous cell carcinoma of the oropharynx

G. Clayman, James Cohen, G. L. Adams

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Neoplastic seeding is a concept of mechanical disruption and spread of tumor into normal tissues. It is well-documented and accepted as an explanation for unusual patterns of tumor recurrence at multiple sites in the body. Neoplastic seeding is often invoked as an explanation for stomal recurrences following treatment of laryngeal carcinoma. However, it is impossible to discern whether these recurrences represent peritracheal lymph nodes, persistent or recurrent local disease, or neoplastic seeding of tumor. The purpose of this article is to report two cases of tracheostomy site recurrences after treatment of oropharyngeal squamous carcinoma, in which neoplastic seeding is the most plausible explanation of recurrence. The rarity of this phenomenon appears strikingly small despite significant experimental evidence supporting the possibility of its occurrence. Although specific recommendations for prevention cannot be made, it appears prudent to avoid re-use of instruments that come into direct contact with squamous cell carcinoma tumor surface.

Original languageEnglish (US)
Pages (from-to)245-248
Number of pages4
JournalHead and Neck
Volume15
Issue number3
StatePublished - 1993

Fingerprint

Oropharynx
Squamous Cell Carcinoma
Recurrence
Neoplasms
Mechanical Phenomena
Tracheostomy
Lymph Nodes
Carcinoma
Therapeutics

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Neoplastic seeding of squamous cell carcinoma of the oropharynx. / Clayman, G.; Cohen, James; Adams, G. L.

In: Head and Neck, Vol. 15, No. 3, 1993, p. 245-248.

Research output: Contribution to journalArticle

Clayman, G, Cohen, J & Adams, GL 1993, 'Neoplastic seeding of squamous cell carcinoma of the oropharynx', Head and Neck, vol. 15, no. 3, pp. 245-248.
Clayman, G. ; Cohen, James ; Adams, G. L. / Neoplastic seeding of squamous cell carcinoma of the oropharynx. In: Head and Neck. 1993 ; Vol. 15, No. 3. pp. 245-248.
@article{ed929ac435aa44218fa8a145236884de,
title = "Neoplastic seeding of squamous cell carcinoma of the oropharynx",
abstract = "Neoplastic seeding is a concept of mechanical disruption and spread of tumor into normal tissues. It is well-documented and accepted as an explanation for unusual patterns of tumor recurrence at multiple sites in the body. Neoplastic seeding is often invoked as an explanation for stomal recurrences following treatment of laryngeal carcinoma. However, it is impossible to discern whether these recurrences represent peritracheal lymph nodes, persistent or recurrent local disease, or neoplastic seeding of tumor. The purpose of this article is to report two cases of tracheostomy site recurrences after treatment of oropharyngeal squamous carcinoma, in which neoplastic seeding is the most plausible explanation of recurrence. The rarity of this phenomenon appears strikingly small despite significant experimental evidence supporting the possibility of its occurrence. Although specific recommendations for prevention cannot be made, it appears prudent to avoid re-use of instruments that come into direct contact with squamous cell carcinoma tumor surface.",
author = "G. Clayman and James Cohen and Adams, {G. L.}",
year = "1993",
language = "English (US)",
volume = "15",
pages = "245--248",
journal = "Head and Neck",
issn = "1043-3074",
publisher = "Wiley-Liss Inc.",
number = "3",

}

TY - JOUR

T1 - Neoplastic seeding of squamous cell carcinoma of the oropharynx

AU - Clayman, G.

AU - Cohen, James

AU - Adams, G. L.

PY - 1993

Y1 - 1993

N2 - Neoplastic seeding is a concept of mechanical disruption and spread of tumor into normal tissues. It is well-documented and accepted as an explanation for unusual patterns of tumor recurrence at multiple sites in the body. Neoplastic seeding is often invoked as an explanation for stomal recurrences following treatment of laryngeal carcinoma. However, it is impossible to discern whether these recurrences represent peritracheal lymph nodes, persistent or recurrent local disease, or neoplastic seeding of tumor. The purpose of this article is to report two cases of tracheostomy site recurrences after treatment of oropharyngeal squamous carcinoma, in which neoplastic seeding is the most plausible explanation of recurrence. The rarity of this phenomenon appears strikingly small despite significant experimental evidence supporting the possibility of its occurrence. Although specific recommendations for prevention cannot be made, it appears prudent to avoid re-use of instruments that come into direct contact with squamous cell carcinoma tumor surface.

AB - Neoplastic seeding is a concept of mechanical disruption and spread of tumor into normal tissues. It is well-documented and accepted as an explanation for unusual patterns of tumor recurrence at multiple sites in the body. Neoplastic seeding is often invoked as an explanation for stomal recurrences following treatment of laryngeal carcinoma. However, it is impossible to discern whether these recurrences represent peritracheal lymph nodes, persistent or recurrent local disease, or neoplastic seeding of tumor. The purpose of this article is to report two cases of tracheostomy site recurrences after treatment of oropharyngeal squamous carcinoma, in which neoplastic seeding is the most plausible explanation of recurrence. The rarity of this phenomenon appears strikingly small despite significant experimental evidence supporting the possibility of its occurrence. Although specific recommendations for prevention cannot be made, it appears prudent to avoid re-use of instruments that come into direct contact with squamous cell carcinoma tumor surface.

UR - http://www.scopus.com/inward/record.url?scp=0027533865&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027533865&partnerID=8YFLogxK

M3 - Article

C2 - 8491588

AN - SCOPUS:0027533865

VL - 15

SP - 245

EP - 248

JO - Head and Neck

JF - Head and Neck

SN - 1043-3074

IS - 3

ER -