Neonatal medical admission in a term and late-preterm cohort exposed to magnesium sulfate

Mara B. Greenberg, Anna A. Penn, Lewis J. Thomas, Yasser Y. El-Sayed, Aaron Caughey, Deirdre J. Lyell

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Objective: The purpose of this study was to estimate neonatal intensive care unit and special care unit (NICU) admission rates and care needs among term and late-preterm neonates who are exposed to antenatal magnesium sulfate. Study Design: We conducted a retrospective cohort study of all singleton neonates of 12 hours exposure, odds ratio, 2.81 (95% confidence interval, 1.316.03); >30 g exposure, odds ratio, 2.59 (95% confidence interval, 1.225.51). Infants in NICU who were diagnosed with hypermagnesemia required fluid or nutritional support more frequently (91.3% vs 39.3%; P <.001) than those without hypermagnesemia. Conclusion: Antenatal magnesium sulfate exposure is associated with NICU admission among term and late-preterm neonates in a dose-dependent fashion. Fluid and nutritional assistance commonly are needed in this cohort.

Original languageEnglish (US)
JournalAmerican Journal of Obstetrics and Gynecology
Volume204
Issue number6
DOIs
StatePublished - Jun 2011

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Magnesium Sulfate
Newborn Infant
Odds Ratio
Confidence Intervals
Nutritional Support
Neonatal Intensive Care Units
Cohort Studies
Retrospective Studies

Keywords

  • antenatal
  • magnesium sulfate exposure
  • neonatal effect

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Neonatal medical admission in a term and late-preterm cohort exposed to magnesium sulfate. / Greenberg, Mara B.; Penn, Anna A.; Thomas, Lewis J.; El-Sayed, Yasser Y.; Caughey, Aaron; Lyell, Deirdre J.

In: American Journal of Obstetrics and Gynecology, Vol. 204, No. 6, 06.2011.

Research output: Contribution to journalArticle

Greenberg, Mara B. ; Penn, Anna A. ; Thomas, Lewis J. ; El-Sayed, Yasser Y. ; Caughey, Aaron ; Lyell, Deirdre J. / Neonatal medical admission in a term and late-preterm cohort exposed to magnesium sulfate. In: American Journal of Obstetrics and Gynecology. 2011 ; Vol. 204, No. 6.
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