Abstract
Objective: The purpose of this study was to estimate neonatal intensive care unit and special care unit (NICU) admission rates and care needs among term and late-preterm neonates who are exposed to antenatal magnesium sulfate. Study Design: We conducted a retrospective cohort study of all singleton neonates of 12 hours exposure, odds ratio, 2.81 (95% confidence interval, 1.316.03); >30 g exposure, odds ratio, 2.59 (95% confidence interval, 1.225.51). Infants in NICU who were diagnosed with hypermagnesemia required fluid or nutritional support more frequently (91.3% vs 39.3%; P <.001) than those without hypermagnesemia. Conclusion: Antenatal magnesium sulfate exposure is associated with NICU admission among term and late-preterm neonates in a dose-dependent fashion. Fluid and nutritional assistance commonly are needed in this cohort.
| Original language | English (US) |
|---|---|
| Journal | American Journal of Obstetrics and Gynecology |
| Volume | 204 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 2011 |
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Keywords
- antenatal
- magnesium sulfate exposure
- neonatal effect
ASJC Scopus subject areas
- Obstetrics and Gynecology
Cite this
Neonatal medical admission in a term and late-preterm cohort exposed to magnesium sulfate. / Greenberg, Mara B.; Penn, Anna A.; Thomas, Lewis J.; El-Sayed, Yasser Y.; Caughey, Aaron; Lyell, Deirdre J.
In: American Journal of Obstetrics and Gynecology, Vol. 204, No. 6, 06.2011.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Neonatal medical admission in a term and late-preterm cohort exposed to magnesium sulfate
AU - Greenberg, Mara B.
AU - Penn, Anna A.
AU - Thomas, Lewis J.
AU - El-Sayed, Yasser Y.
AU - Caughey, Aaron
AU - Lyell, Deirdre J.
PY - 2011/6
Y1 - 2011/6
N2 - Objective: The purpose of this study was to estimate neonatal intensive care unit and special care unit (NICU) admission rates and care needs among term and late-preterm neonates who are exposed to antenatal magnesium sulfate. Study Design: We conducted a retrospective cohort study of all singleton neonates of 12 hours exposure, odds ratio, 2.81 (95% confidence interval, 1.316.03); >30 g exposure, odds ratio, 2.59 (95% confidence interval, 1.225.51). Infants in NICU who were diagnosed with hypermagnesemia required fluid or nutritional support more frequently (91.3% vs 39.3%; P <.001) than those without hypermagnesemia. Conclusion: Antenatal magnesium sulfate exposure is associated with NICU admission among term and late-preterm neonates in a dose-dependent fashion. Fluid and nutritional assistance commonly are needed in this cohort.
AB - Objective: The purpose of this study was to estimate neonatal intensive care unit and special care unit (NICU) admission rates and care needs among term and late-preterm neonates who are exposed to antenatal magnesium sulfate. Study Design: We conducted a retrospective cohort study of all singleton neonates of 12 hours exposure, odds ratio, 2.81 (95% confidence interval, 1.316.03); >30 g exposure, odds ratio, 2.59 (95% confidence interval, 1.225.51). Infants in NICU who were diagnosed with hypermagnesemia required fluid or nutritional support more frequently (91.3% vs 39.3%; P <.001) than those without hypermagnesemia. Conclusion: Antenatal magnesium sulfate exposure is associated with NICU admission among term and late-preterm neonates in a dose-dependent fashion. Fluid and nutritional assistance commonly are needed in this cohort.
KW - antenatal
KW - magnesium sulfate exposure
KW - neonatal effect
UR - http://www.scopus.com/inward/record.url?scp=79958170929&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79958170929&partnerID=8YFLogxK
U2 - 10.1016/j.ajog.2011.01.046
DO - 10.1016/j.ajog.2011.01.046
M3 - Article
C2 - 21376302
AN - SCOPUS:79958170929
VL - 204
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
SN - 0002-9378
IS - 6
ER -