Abstract
Objective: To examine the effect of heart rate characteristics (HRC) monitoring on length of stay among very low birth weight (VLBW; <1500 g birth weight) neonates in the HeRO randomized controlled trial (RCT). Study design: We performed a retrospective analysis of length of stay metrics among 3 subpopulations (all patients, all survivors, and survivors with positive blood or urine cultures) enrolled in a multicenter, RCT of HRC monitoring. Results: Among all patients in the RCT, infants randomized to receive HRC monitoring were more likely than controls to be discharged alive and prior to day 120 (83.6% vs 80.1%, P =.014). The postmenstrual age at discharge for survivors with positive blood or urine cultures was 3.2 days lower among infants randomized to receive HRC monitoring when compared with controls (P =.026). Although there were trends in other metrics toward reduced length of stay in HRC-monitored patients, none reached statistical significance. Conclusions: HRC monitoring is associated with reduced mortality in VLBW patients and a reduction in length of stay among infected surviving VLBW infants. Trial registration: ClinicalTrials.gov: NCT00307333.
Original language | English (US) |
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Pages (from-to) | 162-167 |
Number of pages | 6 |
Journal | Journal of Pediatrics |
Volume | 198 |
DOIs | |
State | Published - Jul 2018 |
Keywords
- UTI
- blood stream infection
- neonate
- sepsis
- very low birth weight
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health