Nanomedicines for Endometriosis: Lessons Learned from Cancer Research

Abraham S. Moses, Ananiya A. Demessie, Olena Taratula, Tetiana Korzun, Ov D. Slayden, Oleh Taratula

    Research output: Contribution to journalReview articlepeer-review

    Abstract

    Endometriosis is an incurable gynecological disease characterized by the abnormal growth of endometrium-like tissue, characteristic of the uterine lining, outside of the uterine cavity. Millions of people with endometriosis suffer from pelvic pain and infertility. This review aims to discuss whether nanomedicines that are promising therapeutic approaches for various diseases have the potential to create a paradigm shift in endometriosis management. For the first time, the available reports and achievements in the field of endometriosis nanomedicine are critically evaluated, and a summary of how nanoparticle-based systems can improve endometriosis treatment and diagnosis is provided. Parallels between cancer and endometriosis are also drawn to understand whether some fundamental principles of the well-established cancer nanomedicine field can be adopted for the development of novel nanoparticle-based strategies for endometriosis. This review provides the state of the art of endometriosis nanomedicine and perspective for researchers aiming to realize and exploit the full potential of nanoparticles for treatment and imaging of the disorder.

    Original languageEnglish (US)
    Article number2004975
    JournalSmall
    Volume17
    Issue number7
    DOIs
    StatePublished - Feb 18 2021

    Keywords

    • endometriosis
    • imaging
    • nanomedicines
    • nanoparticles
    • therapies

    ASJC Scopus subject areas

    • Biotechnology
    • Biomaterials
    • Chemistry(all)
    • Materials Science(all)

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