Myocardial perfusion imaging with colour power doppler contrast echocardiography

R. Senior, P. Soman, R. S. Khattar, A. Lahiri, Sanjiv Kaul

Research output: Contribution to journalArticle

Abstract

The purpose of the study was to determine whether Colour Power- Doppler myocardial contrast echocardiography (MCE) may be used to detect myocardial perfusion using a venous injection of contrast in patients with established coronary artery disease. Fifteen patients with known coronary artery disease and myocardial perfusion defect on Tc-99m sestamibi (MIBI) SPECT underwent MCE within 4 weeks of the SPECT study. Colour Power-Doppler was used in the second harmonic mode to assess myocardial perfusion after peripheral venous injection of BR-1, a new contrast agent. Myocardial perfusion was assessed as present or absent using a 5 segment matching model for both MCE and MIBI SPECT. Of a total of 75 possible segments, 7 (9%) were not analysed because of artefacts during MCE. MIBI showed perfusion defects in 40 out of the 68 analysable segments. There was a concordance of 93% (Kappa=0.85) between MCE and a MIBI SPECT for the detection of perfusion defect in these segments. Concordances between MCE and MIBI SPECT for the identification of perfusion defects in the antero-septal segments was 96% (Kappa=0.92) and infero-lateral segments 93% (Kappa= 0.86). Colour Power-Doppler harmonic imaging during MCE is similar to MIBI SPECT for the detection of myocardial perfusion abnormalities in patients with coronary artery disease.

Original languageEnglish (US)
JournalHeart
Volume79
Issue numberSUPPL. 1
StatePublished - May 1998
Externally publishedYes

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Myocardial Perfusion Imaging
Doppler Echocardiography
Echocardiography
Color
Perfusion
Single-Photon Emission-Computed Tomography
Coronary Artery Disease
Injections
Artifacts
Contrast Media

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Senior, R., Soman, P., Khattar, R. S., Lahiri, A., & Kaul, S. (1998). Myocardial perfusion imaging with colour power doppler contrast echocardiography. Heart, 79(SUPPL. 1).

Myocardial perfusion imaging with colour power doppler contrast echocardiography. / Senior, R.; Soman, P.; Khattar, R. S.; Lahiri, A.; Kaul, Sanjiv.

In: Heart, Vol. 79, No. SUPPL. 1, 05.1998.

Research output: Contribution to journalArticle

Senior, R, Soman, P, Khattar, RS, Lahiri, A & Kaul, S 1998, 'Myocardial perfusion imaging with colour power doppler contrast echocardiography', Heart, vol. 79, no. SUPPL. 1.
Senior R, Soman P, Khattar RS, Lahiri A, Kaul S. Myocardial perfusion imaging with colour power doppler contrast echocardiography. Heart. 1998 May;79(SUPPL. 1).
Senior, R. ; Soman, P. ; Khattar, R. S. ; Lahiri, A. ; Kaul, Sanjiv. / Myocardial perfusion imaging with colour power doppler contrast echocardiography. In: Heart. 1998 ; Vol. 79, No. SUPPL. 1.
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