Abstract
The purpose of the study was to determine whether Colour Power- Doppler myocardial contrast echocardiography (MCE) may be used to detect myocardial perfusion using a venous injection of contrast in patients with established coronary artery disease. Fifteen patients with known coronary artery disease and myocardial perfusion defect on Tc-99m sestamibi (MIBI) SPECT underwent MCE within 4 weeks of the SPECT study. Colour Power-Doppler was used in the second harmonic mode to assess myocardial perfusion after peripheral venous injection of BR-1, a new contrast agent. Myocardial perfusion was assessed as present or absent using a 5 segment matching model for both MCE and MIBI SPECT. Of a total of 75 possible segments, 7 (9%) were not analysed because of artefacts during MCE. MIBI showed perfusion defects in 40 out of the 68 analysable segments. There was a concordance of 93% (Kappa=0.85) between MCE and a MIBI SPECT for the detection of perfusion defect in these segments. Concordances between MCE and MIBI SPECT for the identification of perfusion defects in the antero-septal segments was 96% (Kappa=0.92) and infero-lateral segments 93% (Kappa= 0.86). Colour Power-Doppler harmonic imaging during MCE is similar to MIBI SPECT for the detection of myocardial perfusion abnormalities in patients with coronary artery disease.
| Original language | English (US) |
|---|---|
| Journal | Heart |
| Volume | 79 |
| Issue number | SUPPL. 1 |
| State | Published - May 1998 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Myocardial perfusion imaging with colour power doppler contrast echocardiography. / Senior, R.; Soman, P.; Khattar, R. S.; Lahiri, A.; Kaul, Sanjiv.
In: Heart, Vol. 79, No. SUPPL. 1, 05.1998.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Myocardial perfusion imaging with colour power doppler contrast echocardiography
AU - Senior, R.
AU - Soman, P.
AU - Khattar, R. S.
AU - Lahiri, A.
AU - Kaul, Sanjiv
PY - 1998/5
Y1 - 1998/5
N2 - The purpose of the study was to determine whether Colour Power- Doppler myocardial contrast echocardiography (MCE) may be used to detect myocardial perfusion using a venous injection of contrast in patients with established coronary artery disease. Fifteen patients with known coronary artery disease and myocardial perfusion defect on Tc-99m sestamibi (MIBI) SPECT underwent MCE within 4 weeks of the SPECT study. Colour Power-Doppler was used in the second harmonic mode to assess myocardial perfusion after peripheral venous injection of BR-1, a new contrast agent. Myocardial perfusion was assessed as present or absent using a 5 segment matching model for both MCE and MIBI SPECT. Of a total of 75 possible segments, 7 (9%) were not analysed because of artefacts during MCE. MIBI showed perfusion defects in 40 out of the 68 analysable segments. There was a concordance of 93% (Kappa=0.85) between MCE and a MIBI SPECT for the detection of perfusion defect in these segments. Concordances between MCE and MIBI SPECT for the identification of perfusion defects in the antero-septal segments was 96% (Kappa=0.92) and infero-lateral segments 93% (Kappa= 0.86). Colour Power-Doppler harmonic imaging during MCE is similar to MIBI SPECT for the detection of myocardial perfusion abnormalities in patients with coronary artery disease.
AB - The purpose of the study was to determine whether Colour Power- Doppler myocardial contrast echocardiography (MCE) may be used to detect myocardial perfusion using a venous injection of contrast in patients with established coronary artery disease. Fifteen patients with known coronary artery disease and myocardial perfusion defect on Tc-99m sestamibi (MIBI) SPECT underwent MCE within 4 weeks of the SPECT study. Colour Power-Doppler was used in the second harmonic mode to assess myocardial perfusion after peripheral venous injection of BR-1, a new contrast agent. Myocardial perfusion was assessed as present or absent using a 5 segment matching model for both MCE and MIBI SPECT. Of a total of 75 possible segments, 7 (9%) were not analysed because of artefacts during MCE. MIBI showed perfusion defects in 40 out of the 68 analysable segments. There was a concordance of 93% (Kappa=0.85) between MCE and a MIBI SPECT for the detection of perfusion defect in these segments. Concordances between MCE and MIBI SPECT for the identification of perfusion defects in the antero-septal segments was 96% (Kappa=0.92) and infero-lateral segments 93% (Kappa= 0.86). Colour Power-Doppler harmonic imaging during MCE is similar to MIBI SPECT for the detection of myocardial perfusion abnormalities in patients with coronary artery disease.
UR - http://www.scopus.com/inward/record.url?scp=33751393693&partnerID=8YFLogxK
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M3 - Article
VL - 79
JO - Heart
JF - Heart
SN - 1355-6037
IS - SUPPL. 1
ER -