Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic ras is a dominant predictor for resistance

Nathan T. Ihle, Robert Lemos, Peter Wipf, Adly Yacoub, Clint Mitchell, Doris Siwak, Gordon B. Mills, Paul Dent, D. Lynn Kirkpatrick, Garth Powis

Research output: Contribution to journalArticlepeer-review

250 Scopus citations

Fingerprint

Dive into the research topics of 'Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic ras is a dominant predictor for resistance'. Together they form a unique fingerprint.

Medicine & Life Sciences