TY - JOUR
T1 - Mutant analysis shows that the Ca2+-induced K+ current shuts off one type of excitation in Paramecium.
AU - Saimi, Y.
AU - Hinrichsen, R. D.
AU - Forte, M.
AU - Kung, C.
PY - 1983/8
Y1 - 1983/8
N2 - Two mutants of Paramecium tetraurelia, called "pantophobiacs," were found to lack most of the slow Ca2+-induced K+ outward current. Passive properties, the transient Ca2+ inward current, and the fast depolarization-induced K+ outward current remain normal. The mutant defect reduces the ability to shut off a normal, excited state of the membrane and results in repeated, long backward swimming instead of the wild-type jerks in response to a variety of ions, to heat, and to touch.
AB - Two mutants of Paramecium tetraurelia, called "pantophobiacs," were found to lack most of the slow Ca2+-induced K+ outward current. Passive properties, the transient Ca2+ inward current, and the fast depolarization-induced K+ outward current remain normal. The mutant defect reduces the ability to shut off a normal, excited state of the membrane and results in repeated, long backward swimming instead of the wild-type jerks in response to a variety of ions, to heat, and to touch.
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U2 - 10.1073/pnas.80.16.5112
DO - 10.1073/pnas.80.16.5112
M3 - Article
C2 - 6410401
AN - SCOPUS:0020805513
SN - 0027-8424
VL - 80
SP - 5112
EP - 5116
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 16
ER -