Multifunctional catheters combining intracardiac ultrasound imaging and electrophysiology sensing

Douglas N. Stephens, Jonathan Cannata, Ruibin Liu, Jian Zhong Zhao, K. Kirk Shung, Hien Nguyen, Raymond Chia, Aaron Dentinger, Douglas Wildes, Kai E. Thomenius, Aman Mahajan, Kalyanam Shivkumar, Kang Kim, Matthew O'Donnell, Amin Nikoozadeh, Omer Oralkan, Pierre T. Khuri-Yakub, David Sahn

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A family of 3 multifunctional intracardiac imaging and electrophysiology (EP) mapping catheters has been in development to help guide diagnostic and therapeutic intracardiac EP procedures. The catheter tip on the first device includes a 7.5 MHz, 64-element, side-looking phased array for high resolution sector scanning. The second device is a forward-looking catheter with a 24-element 14 MHz phased array. Both of these catheters operate on a commercial imaging system with standard software. Multiple EP mapping sensors were mounted as ring electrodes near the arrays for electrocardiographic synchronization of ultrasound images and used for unique integration with EP mapping technologies. To help establish the catheters' ability for integration with EP interventional procedures, tests were performed in vivo in a porcine animal model to demonstrate both useful intracardiac echocardiographic (ICE) visualization and simultaneous 3-D positional information using integrated electroanatomical mapping techniques. The catheters also performed well in high frame rate imaging, color now imaging, and strain rate imaging of atrial and ventricular structures. The companion paper of this work discusses the catheter design of the side-looking catheter with special attention to acoustic lens design. The third device in development is a 10 MHz forward-looking ring array that is to be mounted at the distal tip of a 9F catheter to permit use of the available catheter lumen for adjunctive therapy tools.

Original languageEnglish (US)
Article number4559656
Pages (from-to)1570-1581
Number of pages12
JournalIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Volume55
Issue number7
DOIs
StatePublished - Jul 2008

Fingerprint

electrophysiology
Electrophysiology
Catheters
Ultrasonics
Imaging techniques
phased arrays
lens design
animal models
lumens
rings
strain rate
therapy
synchronism
sectors
Acoustic imaging
computer programs
color
scanning
electrodes
acoustics

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Acoustics and Ultrasonics
  • Instrumentation

Cite this

Multifunctional catheters combining intracardiac ultrasound imaging and electrophysiology sensing. / Stephens, Douglas N.; Cannata, Jonathan; Liu, Ruibin; Zhao, Jian Zhong; Shung, K. Kirk; Nguyen, Hien; Chia, Raymond; Dentinger, Aaron; Wildes, Douglas; Thomenius, Kai E.; Mahajan, Aman; Shivkumar, Kalyanam; Kim, Kang; O'Donnell, Matthew; Nikoozadeh, Amin; Oralkan, Omer; Khuri-Yakub, Pierre T.; Sahn, David.

In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Vol. 55, No. 7, 4559656, 07.2008, p. 1570-1581.

Research output: Contribution to journalArticle

Stephens, DN, Cannata, J, Liu, R, Zhao, JZ, Shung, KK, Nguyen, H, Chia, R, Dentinger, A, Wildes, D, Thomenius, KE, Mahajan, A, Shivkumar, K, Kim, K, O'Donnell, M, Nikoozadeh, A, Oralkan, O, Khuri-Yakub, PT & Sahn, D 2008, 'Multifunctional catheters combining intracardiac ultrasound imaging and electrophysiology sensing', IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 55, no. 7, 4559656, pp. 1570-1581. https://doi.org/10.1109/TUFFC.2008.834
Stephens, Douglas N. ; Cannata, Jonathan ; Liu, Ruibin ; Zhao, Jian Zhong ; Shung, K. Kirk ; Nguyen, Hien ; Chia, Raymond ; Dentinger, Aaron ; Wildes, Douglas ; Thomenius, Kai E. ; Mahajan, Aman ; Shivkumar, Kalyanam ; Kim, Kang ; O'Donnell, Matthew ; Nikoozadeh, Amin ; Oralkan, Omer ; Khuri-Yakub, Pierre T. ; Sahn, David. / Multifunctional catheters combining intracardiac ultrasound imaging and electrophysiology sensing. In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 2008 ; Vol. 55, No. 7. pp. 1570-1581.
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