Multidisciplinary management of acromegaly: A consensus

Andrea Giustina; Garni Barkhoudarian; Albert Beckers; Anat Ben-Shlomo; Nienke Biermasz; Beverly Biller; Cesar Boguszewski; Marek Bolanowski; Jens Bollerslev; Vivien Bonert; Marcello D. Bronstein; Michael Buchfelder; Felipe Casanueva; Philippe Chanson; David Clemmons; Maria Fleseriu; Anna Maria Formenti; Pamela Freda; Monica Gadelha; Eliza Geer; Mark Gurnell; Anthony P. Heaney; Ken K.Y. Ho; Adriana G. Ioachimescu; Steven Lamberts; Edward Laws; Marco Losa; Pietro Maffei; Adam Mamelak; Moises Mercado; Mark Molitch; Pietro Mortini; Alberto M. Pereira; Stephan Petersenn; Kalmon Post; Manuel Puig-Domingo; Roberto Salvatori; Susan L. Samson; Ilan Shimon; Christian Strasburger; Brooke Swearingen; Peter Trainer; Mary L. Vance; John Wass; Margaret E. Wierman; Kevin C.J. Yuen; Maria Chiara Zatelli; Shlomo Melmed

doi:10.1007/s11154-020-09588-z

Multidisciplinary management of acromegaly: A consensus

Andrea Giustina, Garni Barkhoudarian, Albert Beckers, Anat Ben-Shlomo, Nienke Biermasz, Beverly Biller, Cesar Boguszewski, Marek Bolanowski, Jens Bollerslev, Vivien Bonert, Marcello D. Bronstein, Michael Buchfelder, Felipe Casanueva, Philippe Chanson, David Clemmons, Maria Fleseriu, Anna Maria Formenti, Pamela Freda, Monica Gadelha, Eliza GeerMark Gurnell, Anthony P. Heaney, Ken K.Y. Ho, Adriana G. Ioachimescu, Steven Lamberts, Edward Laws, Marco Losa, Pietro Maffei, Adam Mamelak, Moises Mercado, Mark Molitch, Pietro Mortini, Alberto M. Pereira, Stephan Petersenn, Kalmon Post, Manuel Puig-Domingo, Roberto Salvatori, Susan L. Samson, Ilan Shimon, Christian Strasburger, Brooke Swearingen, Peter Trainer, Mary L. Vance, John Wass, Margaret E. Wierman, Kevin C.J. Yuen, Maria Chiara Zatelli, Shlomo Melmed

Research output: Contribution to journal › Review article › peer-review

98 Scopus citations

Abstract

The 13th Acromegaly Consensus Conference was held in November 2019 in Fort Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and neurosurgeons who considered optimal approaches for multidisciplinary acromegaly management. Focused discussions reviewed techniques, results, and side effects of surgery, radiotherapy, and medical therapy, and how advances in technology and novel techniques have changed the way these modalities are used alone or in combination. Effects of treatment on patient outcomes were considered, along with strategies for optimizing and personalizing therapeutic approaches. Expert consensus recommendations emphasize how best to implement available treatment options as part of a multidisciplinary approach at Pituitary Tumor Centers of Excellence.

Original language	English (US)
Pages (from-to)	667-678
Number of pages	12
Journal	Reviews in Endocrine and Metabolic Disorders
Volume	21
Issue number	4
DOIs	https://doi.org/10.1007/s11154-020-09588-z
State	Published - Dec 1 2020

Keywords

Acromegaly
Consensus
Medical therapy
Multidisciplinary management
Pituitary tumor centers of excellence
Radiotherapy
Surgery

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1007/s11154-020-09588-z

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Giustina, A., Barkhoudarian, G., Beckers, A., Ben-Shlomo, A., Biermasz, N., Biller, B., Boguszewski, C., Bolanowski, M., Bollerslev, J., Bonert, V., Bronstein, M. D., Buchfelder, M., Casanueva, F., Chanson, P., Clemmons, D., Fleseriu, M., Formenti, A. M., Freda, P., Gadelha, M., ... Melmed, S. (2020). Multidisciplinary management of acromegaly: A consensus. Reviews in Endocrine and Metabolic Disorders, 21(4), 667-678. https://doi.org/10.1007/s11154-020-09588-z

Giustina, A, Barkhoudarian, G, Beckers, A, Ben-Shlomo, A, Biermasz, N, Biller, B, Boguszewski, C, Bolanowski, M, Bollerslev, J, Bonert, V, Bronstein, MD, Buchfelder, M, Casanueva, F, Chanson, P, Clemmons, D, Fleseriu, M, Formenti, AM, Freda, P, Gadelha, M, Geer, E, Gurnell, M, Heaney, AP, Ho, KKY, Ioachimescu, AG, Lamberts, S, Laws, E, Losa, M, Maffei, P, Mamelak, A, Mercado, M, Molitch, M, Mortini, P, Pereira, AM, Petersenn, S, Post, K, Puig-Domingo, M, Salvatori, R, Samson, SL, Shimon, I, Strasburger, C, Swearingen, B, Trainer, P, Vance, ML, Wass, J, Wierman, ME, Yuen, KCJ, Zatelli, MC & Melmed, S 2020, 'Multidisciplinary management of acromegaly: A consensus', Reviews in Endocrine and Metabolic Disorders, vol. 21, no. 4, pp. 667-678. https://doi.org/10.1007/s11154-020-09588-z

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abstract = "The 13th Acromegaly Consensus Conference was held in November 2019 in Fort Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and neurosurgeons who considered optimal approaches for multidisciplinary acromegaly management. Focused discussions reviewed techniques, results, and side effects of surgery, radiotherapy, and medical therapy, and how advances in technology and novel techniques have changed the way these modalities are used alone or in combination. Effects of treatment on patient outcomes were considered, along with strategies for optimizing and personalizing therapeutic approaches. Expert consensus recommendations emphasize how best to implement available treatment options as part of a multidisciplinary approach at Pituitary Tumor Centers of Excellence.",

keywords = "Acromegaly, Consensus, Medical therapy, Multidisciplinary management, Pituitary tumor centers of excellence, Radiotherapy, Surgery",

author = "Andrea Giustina and Garni Barkhoudarian and Albert Beckers and Anat Ben-Shlomo and Nienke Biermasz and Beverly Biller and Cesar Boguszewski and Marek Bolanowski and Jens Bollerslev and Vivien Bonert and Bronstein, {Marcello D.} and Michael Buchfelder and Felipe Casanueva and Philippe Chanson and David Clemmons and Maria Fleseriu and Formenti, {Anna Maria} and Pamela Freda and Monica Gadelha and Eliza Geer and Mark Gurnell and Heaney, {Anthony P.} and Ho, {Ken K.Y.} and Ioachimescu, {Adriana G.} and Steven Lamberts and Edward Laws and Marco Losa and Pietro Maffei and Adam Mamelak and Moises Mercado and Mark Molitch and Pietro Mortini and Pereira, {Alberto M.} and Stephan Petersenn and Kalmon Post and Manuel Puig-Domingo and Roberto Salvatori and Samson, {Susan L.} and Ilan Shimon and Christian Strasburger and Brooke Swearingen and Peter Trainer and Vance, {Mary L.} and John Wass and Wierman, {Margaret E.} and Yuen, {Kevin C.J.} and Zatelli, {Maria Chiara} and Shlomo Melmed",

note = "Funding Information: PUF has received research grant to her institution for clinical research studies from Pfizer, Novartis, Ipsen and Chiasma. Funding Information: The 13th Acromegaly Consensus Conference was supported by unrestricted educational grants from Ipsen and Pfizer Inc. Scientific sponsorship of the meeting was provided by Cedars-Sinai Medical Center, Los Angeles, CA. Funding Information: PC has received unrestricted research and educational grants from Ipsen, Novartis, Crinetics and Pfizer on behalf of the Service of Endocrinology and Reproductive Diseases, H{\^o}pitaux Universitaires Paris-Saclay and Association Recherche Endocrinologie Bic{\^e}tre, and has served as investigator (principal or coordinator) for clinical trials funded by Novartis, Pfizer, Ipsen, Italpharmaco, Chiasma. PC gave lectures for Ipsen, Novartis, and Pfizer. All the fees and honoraria are paid to his Institution or Research Association. Publisher Copyright: {\textcopyright} 2020, Springer Science+Business Media, LLC, part of Springer Nature.",

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doi = "10.1007/s11154-020-09588-z",

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AU - Biermasz, Nienke

AU - Biller, Beverly

AU - Boguszewski, Cesar

AU - Bolanowski, Marek

AU - Bollerslev, Jens

AU - Bonert, Vivien

AU - Bronstein, Marcello D.

AU - Buchfelder, Michael

AU - Casanueva, Felipe

AU - Chanson, Philippe

AU - Clemmons, David

AU - Fleseriu, Maria

AU - Formenti, Anna Maria

AU - Freda, Pamela

AU - Gadelha, Monica

AU - Geer, Eliza

AU - Gurnell, Mark

AU - Heaney, Anthony P.

AU - Ho, Ken K.Y.

AU - Ioachimescu, Adriana G.

AU - Lamberts, Steven

AU - Laws, Edward

AU - Losa, Marco

AU - Maffei, Pietro

AU - Mamelak, Adam

AU - Mercado, Moises

AU - Molitch, Mark

AU - Mortini, Pietro

AU - Pereira, Alberto M.

AU - Petersenn, Stephan

AU - Post, Kalmon

AU - Puig-Domingo, Manuel

AU - Salvatori, Roberto

AU - Samson, Susan L.

AU - Shimon, Ilan

AU - Strasburger, Christian

AU - Swearingen, Brooke

AU - Trainer, Peter

AU - Vance, Mary L.

AU - Wass, John

AU - Wierman, Margaret E.

AU - Yuen, Kevin C.J.

AU - Zatelli, Maria Chiara

AU - Melmed, Shlomo

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KW - Medical therapy

KW - Multidisciplinary management

KW - Pituitary tumor centers of excellence

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Multidisciplinary management of acromegaly: A consensus

Abstract

Keywords

ASJC Scopus subject areas

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