mRNA Coronavirus Disease 2019 Vaccine-Associated Myopericarditis in Adolescents: A Survey Study

Utkarsh Kohli; Lavina Desai; Devyani Chowdhury; Ashraf S. Harahsheh; Alexandra B. Yonts; Annette Ansong; Arash Sabati; Hoang H. Nguyen; Tarique Hussain; Danyal Khan; David A. Parra; Jennifer A. Su; Jyoti K. Patel; Christina Ronai; Monique Bohun; Bishara J. Freij; Matthew J. O'Connor; Joseph W. Rosanno; Aamisha Gupta; Arash Salavitabar; Adam L. Dorfman; Jesse Hansen; Olivia Frosch; Elizabeth L. Profita; Shiraz Maskatia; Deepika Thacker; Shubhika Shrivastava; Tyler H. Harris; Brian Feingold; Stuart Berger; Michael Campbell; Salim F. Idriss; Srikant Das; Markus S. Renno; Ken Knecht; S. Yukiko Asaki; Sunil Patel; Ravi Ashwath; Renata Shih; John Phillips; Bibhuti Das; Preeti Ramachandran; Eyal Sagiv; Aarti H. Bhat; Jonathan N. Johnson; Nathaniel W. Taggart; Jason Imundo; Natasha Nakra; Shashank Behere; Anjlee Patel; Avichal Aggarwal; Saif Aljemmali; Sean Lang; Sarosh P. Batlivala; Daniel E. Forsha; Gregory P. Conners; Jana Shaw; Frank C. Smith; Linda Pauliks; Joseph Vettukattil; Kenneth Shaffer; Stefanie Cheang; Sonia Voleti; Rajesh Shenoy; Rukmini Komarlu; Shea J. Ryan; Christopher Snyder; Neha Bansal; Madhu Sharma; Jeffrey A. Robinson; Sandra R. Arnold; Christine M. Salvatore; Madan Kumar; Michael A. Fremed; Julie S. Glickstein; Melissa Perrotta; William Orr; Tamika Rozema; Muthayipalayam Thirumoorthi; Charles J. Mullett; Jocelyn Y. Ang

doi:10.1016/j.jpeds.2021.12.025

mRNA Coronavirus Disease 2019 Vaccine-Associated Myopericarditis in Adolescents: A Survey Study

Utkarsh Kohli, Lavina Desai, Devyani Chowdhury, Ashraf S. Harahsheh, Alexandra B. Yonts, Annette Ansong, Arash Sabati, Hoang H. Nguyen, Tarique Hussain, Danyal Khan, David A. Parra, Jennifer A. Su, Jyoti K. Patel, Christina Ronai, Monique Bohun, Bishara J. Freij, Matthew J. O'Connor, Joseph W. Rosanno, Aamisha Gupta, Arash SalavitabarAdam L. Dorfman, Jesse Hansen, Olivia Frosch, Elizabeth L. Profita, Shiraz Maskatia, Deepika Thacker, Shubhika Shrivastava, Tyler H. Harris, Brian Feingold, Stuart Berger, Michael Campbell, Salim F. Idriss, Srikant Das, Markus S. Renno, Ken Knecht, S. Yukiko Asaki, Sunil Patel, Ravi Ashwath, Renata Shih, John Phillips, Bibhuti Das, Preeti Ramachandran, Eyal Sagiv, Aarti H. Bhat, Jonathan N. Johnson, Nathaniel W. Taggart, Jason Imundo, Natasha Nakra, Shashank Behere, Anjlee Patel, Avichal Aggarwal, Saif Aljemmali, Sean Lang, Sarosh P. Batlivala, Daniel E. Forsha, Gregory P. Conners, Jana Shaw, Frank C. Smith, Linda Pauliks, Joseph Vettukattil, Kenneth Shaffer, Stefanie Cheang, Sonia Voleti, Rajesh Shenoy, Rukmini Komarlu, Shea J. Ryan, Christopher Snyder, Neha Bansal, Madhu Sharma, Jeffrey A. Robinson, Sandra R. Arnold, Christine M. Salvatore, Madan Kumar, Michael A. Fremed, Julie S. Glickstein, Melissa Perrotta, William Orr, Tamika Rozema, Muthayipalayam Thirumoorthi, Charles J. Mullett, Jocelyn Y. Ang

Pediatrics

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

In this survey study of institutions across the US, marked variability in evaluation, treatment, and follow-up of adolescents 12 through 18 years of age with mRNA coronavirus disease 2019 (COVID-19) vaccine-associated myopericarditis was noted. Only one adolescent with life-threatening complications was reported, with no deaths at any of the participating institutions.

Original language	English (US)
Pages (from-to)	208-213.e3
Journal	Journal of Pediatrics
Volume	243
DOIs	https://doi.org/10.1016/j.jpeds.2021.12.025
State	Published - Apr 2022

Keywords

mRNA COVID-19 vaccine-associated myopericarditis
outcomes
survey
variability

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

Access to Document

10.1016/j.jpeds.2021.12.025

Cite this

Kohli, U., Desai, L., Chowdhury, D., Harahsheh, A. S., Yonts, A. B., Ansong, A., Sabati, A., Nguyen, H. H., Hussain, T., Khan, D., Parra, D. A., Su, J. A., Patel, J. K., Ronai, C., Bohun, M., Freij, B. J., O'Connor, M. J., Rosanno, J. W., Gupta, A., ... Ang, J. Y. (2022). mRNA Coronavirus Disease 2019 Vaccine-Associated Myopericarditis in Adolescents: A Survey Study. Journal of Pediatrics, 243, 208-213.e3. https://doi.org/10.1016/j.jpeds.2021.12.025

Kohli, U, Desai, L, Chowdhury, D, Harahsheh, AS, Yonts, AB, Ansong, A, Sabati, A, Nguyen, HH, Hussain, T, Khan, D, Parra, DA, Su, JA, Patel, JK, Ronai, C, Bohun, M, Freij, BJ, O'Connor, MJ, Rosanno, JW, Gupta, A, Salavitabar, A, Dorfman, AL, Hansen, J, Frosch, O, Profita, EL, Maskatia, S, Thacker, D, Shrivastava, S, Harris, TH, Feingold, B, Berger, S, Campbell, M, Idriss, SF, Das, S, Renno, MS, Knecht, K, Asaki, SY, Patel, S, Ashwath, R, Shih, R, Phillips, J, Das, B, Ramachandran, P, Sagiv, E, Bhat, AH, Johnson, JN, Taggart, NW, Imundo, J, Nakra, N, Behere, S, Patel, A, Aggarwal, A, Aljemmali, S, Lang, S, Batlivala, SP, Forsha, DE, Conners, GP, Shaw, J, Smith, FC, Pauliks, L, Vettukattil, J, Shaffer, K, Cheang, S, Voleti, S, Shenoy, R, Komarlu, R, Ryan, SJ, Snyder, C, Bansal, N, Sharma, M, Robinson, JA, Arnold, SR, Salvatore, CM, Kumar, M, Fremed, MA, Glickstein, JS, Perrotta, M, Orr, W, Rozema, T, Thirumoorthi, M, Mullett, CJ & Ang, JY 2022, 'mRNA Coronavirus Disease 2019 Vaccine-Associated Myopericarditis in Adolescents: A Survey Study', Journal of Pediatrics, vol. 243, pp. 208-213.e3. https://doi.org/10.1016/j.jpeds.2021.12.025

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title = "mRNA Coronavirus Disease 2019 Vaccine-Associated Myopericarditis in Adolescents: A Survey Study",

abstract = "In this survey study of institutions across the US, marked variability in evaluation, treatment, and follow-up of adolescents 12 through 18 years of age with mRNA coronavirus disease 2019 (COVID-19) vaccine-associated myopericarditis was noted. Only one adolescent with life-threatening complications was reported, with no deaths at any of the participating institutions.",

keywords = "mRNA COVID-19 vaccine-associated myopericarditis, outcomes, survey, variability",

author = "Utkarsh Kohli and Lavina Desai and Devyani Chowdhury and Harahsheh, {Ashraf S.} and Yonts, {Alexandra B.} and Annette Ansong and Arash Sabati and Nguyen, {Hoang H.} and Tarique Hussain and Danyal Khan and Parra, {David A.} and Su, {Jennifer A.} and Patel, {Jyoti K.} and Christina Ronai and Monique Bohun and Freij, {Bishara J.} and O'Connor, {Matthew J.} and Rosanno, {Joseph W.} and Aamisha Gupta and Arash Salavitabar and Dorfman, {Adam L.} and Jesse Hansen and Olivia Frosch and Profita, {Elizabeth L.} and Shiraz Maskatia and Deepika Thacker and Shubhika Shrivastava and Harris, {Tyler H.} and Brian Feingold and Stuart Berger and Michael Campbell and Idriss, {Salim F.} and Srikant Das and Renno, {Markus S.} and Ken Knecht and Asaki, {S. Yukiko} and Sunil Patel and Ravi Ashwath and Renata Shih and John Phillips and Bibhuti Das and Preeti Ramachandran and Eyal Sagiv and Bhat, {Aarti H.} and Johnson, {Jonathan N.} and Taggart, {Nathaniel W.} and Jason Imundo and Natasha Nakra and Shashank Behere and Anjlee Patel and Avichal Aggarwal and Saif Aljemmali and Sean Lang and Batlivala, {Sarosh P.} and Forsha, {Daniel E.} and Conners, {Gregory P.} and Jana Shaw and Smith, {Frank C.} and Linda Pauliks and Joseph Vettukattil and Kenneth Shaffer and Stefanie Cheang and Sonia Voleti and Rajesh Shenoy and Rukmini Komarlu and Ryan, {Shea J.} and Christopher Snyder and Neha Bansal and Madhu Sharma and Robinson, {Jeffrey A.} and Arnold, {Sandra R.} and Salvatore, {Christine M.} and Madan Kumar and Fremed, {Michael A.} and Glickstein, {Julie S.} and Melissa Perrotta and William Orr and Tamika Rozema and Muthayipalayam Thirumoorthi and Mullett, {Charles J.} and Ang, {Jocelyn Y.}",

note = "Funding Information: A.H. is supported by a Sub-agreement from the Johns Hopkins University with funds provided by R61HD105591 from the Eunice Kennedy Shriver National Institute of Child Health & Human Development and the Office of the Director, National Institute of Health (OD). This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Eunice Kennedy Shriver National Institute of Child Health & Human Development, the Office of the Director, National Institutes of Health (OD), the National Institutes of Health, the National Institute of Biomedical Imaging and Bioengineering, the National Heart, Lung, and Blood Institute, or the Johns Hopkins University. The authors declare no conflicts of interest. Funding Information: A.H. is supported by a Sub-agreement from the Johns Hopkins University with funds provided by R61HD105591 from the Eunice Kennedy Shriver National Institute of Child Health & Human Development and the Office of the Director, National Institute of Health (OD). This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Eunice Kennedy Shriver National Institute of Child Health & Human Development, the Office of the Director, National Institutes of Health (OD), the National Institutes of Health, the National Institute of Biomedical Imaging and Bioengineering, the National Heart, Lung, and Blood Institute, or the Johns Hopkins University. The authors declare no conflicts of interest. Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",

year = "2022",

month = apr,

doi = "10.1016/j.jpeds.2021.12.025",

language = "English (US)",

volume = "243",

pages = "208--213.e3",

journal = "Journal of Pediatrics",

issn = "0022-3476",

publisher = "Mosby Inc.",

}

TY - JOUR

T1 - mRNA Coronavirus Disease 2019 Vaccine-Associated Myopericarditis in Adolescents

T2 - A Survey Study

AU - Kohli, Utkarsh

AU - Desai, Lavina

AU - Chowdhury, Devyani

AU - Harahsheh, Ashraf S.

AU - Yonts, Alexandra B.

AU - Ansong, Annette

AU - Sabati, Arash

AU - Nguyen, Hoang H.

AU - Hussain, Tarique

AU - Khan, Danyal

AU - Parra, David A.

AU - Su, Jennifer A.

AU - Patel, Jyoti K.

AU - Ronai, Christina

AU - Bohun, Monique

AU - Freij, Bishara J.

AU - O'Connor, Matthew J.

AU - Rosanno, Joseph W.

AU - Gupta, Aamisha

AU - Salavitabar, Arash

AU - Dorfman, Adam L.

AU - Hansen, Jesse

AU - Frosch, Olivia

AU - Profita, Elizabeth L.

AU - Maskatia, Shiraz

AU - Thacker, Deepika

AU - Shrivastava, Shubhika

AU - Harris, Tyler H.

AU - Feingold, Brian

AU - Berger, Stuart

AU - Campbell, Michael

AU - Idriss, Salim F.

AU - Das, Srikant

AU - Renno, Markus S.

AU - Knecht, Ken

AU - Asaki, S. Yukiko

AU - Patel, Sunil

AU - Ashwath, Ravi

AU - Shih, Renata

AU - Phillips, John

AU - Das, Bibhuti

AU - Ramachandran, Preeti

AU - Sagiv, Eyal

AU - Bhat, Aarti H.

AU - Johnson, Jonathan N.

AU - Taggart, Nathaniel W.

AU - Imundo, Jason

AU - Nakra, Natasha

AU - Behere, Shashank

AU - Patel, Anjlee

AU - Aggarwal, Avichal

AU - Aljemmali, Saif

AU - Lang, Sean

AU - Batlivala, Sarosh P.

AU - Forsha, Daniel E.

AU - Conners, Gregory P.

AU - Shaw, Jana

AU - Smith, Frank C.

AU - Pauliks, Linda

AU - Vettukattil, Joseph

AU - Shaffer, Kenneth

AU - Cheang, Stefanie

AU - Voleti, Sonia

AU - Shenoy, Rajesh

AU - Komarlu, Rukmini

AU - Ryan, Shea J.

AU - Snyder, Christopher

AU - Bansal, Neha

AU - Sharma, Madhu

AU - Robinson, Jeffrey A.

AU - Arnold, Sandra R.

AU - Salvatore, Christine M.

AU - Kumar, Madan

AU - Fremed, Michael A.

AU - Glickstein, Julie S.

AU - Perrotta, Melissa

AU - Orr, William

AU - Rozema, Tamika

AU - Thirumoorthi, Muthayipalayam

AU - Mullett, Charles J.

AU - Ang, Jocelyn Y.

N1 - Funding Information: A.H. is supported by a Sub-agreement from the Johns Hopkins University with funds provided by R61HD105591 from the Eunice Kennedy Shriver National Institute of Child Health & Human Development and the Office of the Director, National Institute of Health (OD). This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Eunice Kennedy Shriver National Institute of Child Health & Human Development, the Office of the Director, National Institutes of Health (OD), the National Institutes of Health, the National Institute of Biomedical Imaging and Bioengineering, the National Heart, Lung, and Blood Institute, or the Johns Hopkins University. The authors declare no conflicts of interest. Funding Information: A.H. is supported by a Sub-agreement from the Johns Hopkins University with funds provided by R61HD105591 from the Eunice Kennedy Shriver National Institute of Child Health & Human Development and the Office of the Director, National Institute of Health (OD). This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Eunice Kennedy Shriver National Institute of Child Health & Human Development, the Office of the Director, National Institutes of Health (OD), the National Institutes of Health, the National Institute of Biomedical Imaging and Bioengineering, the National Heart, Lung, and Blood Institute, or the Johns Hopkins University. The authors declare no conflicts of interest. Publisher Copyright: © 2021 Elsevier Inc.

PY - 2022/4

Y1 - 2022/4

N2 - In this survey study of institutions across the US, marked variability in evaluation, treatment, and follow-up of adolescents 12 through 18 years of age with mRNA coronavirus disease 2019 (COVID-19) vaccine-associated myopericarditis was noted. Only one adolescent with life-threatening complications was reported, with no deaths at any of the participating institutions.

AB - In this survey study of institutions across the US, marked variability in evaluation, treatment, and follow-up of adolescents 12 through 18 years of age with mRNA coronavirus disease 2019 (COVID-19) vaccine-associated myopericarditis was noted. Only one adolescent with life-threatening complications was reported, with no deaths at any of the participating institutions.

KW - mRNA COVID-19 vaccine-associated myopericarditis

KW - outcomes

KW - survey

KW - variability

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U2 - 10.1016/j.jpeds.2021.12.025

DO - 10.1016/j.jpeds.2021.12.025

M3 - Article

C2 - 34952008

AN - SCOPUS:85123350478

VL - 243

SP - 208-213.e3

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

ER -

mRNA Coronavirus Disease 2019 Vaccine-Associated Myopericarditis in Adolescents: A Survey Study

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