MR imaging and MR spectroscopic imaging of prostate cancer

Arumugam Rajesh, Fergus Coakley

Research output: Contribution to journalArticle

37 Scopus citations


The primary indication for prostate MR imaging and MR spectroscopic imaging is the evaluation of men with newly diagnosed prostate cancer with a moderate or high risk for extracapsular extension who are uncertain whether to go undergo surgery or radiotherapy. Other applications of MR imaging and MR spectroscopic imaging in prostate cancer are under investigation and are yet to be defined fully. Areas of active research interest include volumetric localization of prostate cancer, in vivo MR spectroscopic imaging findings at high field strength (3 T), in vitro MR spectroscopic imaging findings at very high field strength (711T), novel spectroscopic markers of malignancy such as polyamines and spermine, and interventional MR guidance of biopsy and therapy [39,80,81]. MR spectroscopic imaging remains a relatively novel technique, and successful implementation is demanding in terms of adequate fat and water suppression, postprocessing, and coverage. Nonetheless, only MR imaging and MR spectroscopic imaging allow combined structural and metabolic evaluation of prostate cancer location, aggressiveness, and stage, and MR imaging provides clinically and therapeutically relevant information on prostatic and periprostatic anatomy. The technology remains in evolution, and continued advances in accuracy and utility are likely.

Original languageEnglish (US)
Pages (from-to)557-579
Number of pages23
JournalMagnetic Resonance Imaging Clinics of North America
Issue number3
Publication statusPublished - Aug 2004
Externally publishedYes


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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