Motor fluctuations and dyskinesia in Parkinson's disease

John G. Nutt

doi:10.1016/S1353-8020(01)00024-4

Motor fluctuations and dyskinesia in Parkinson's disease

John G. Nutt

Neurology

Research output: Contribution to journal › Article › peer-review

93 Scopus citations

Abstract

Motor fluctuations and dyskinesia are common complications of long-term levodopa therapy. The neural and molecular mechanisms underlying their development are partially understood. A variety of clinical strategies may reduce the unpredictability of motor fluctuations and reduce their impact. Prevention of these complications remains an elusive goal.

Original language	English (US)
Pages (from-to)	101-108
Number of pages	8
Journal	Parkinsonism and Related Disorders
Volume	8
Issue number	2
DOIs	https://doi.org/10.1016/S1353-8020(01)00024-4
State	Published - 2001

Keywords

Levodopa
Levodopa-induced dyskinesia
Motor fluctuations
Parkinson's disease

ASJC Scopus subject areas

Neurology
Geriatrics and Gerontology
Clinical Neurology

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10.1016/S1353-8020(01)00024-4

Cite this

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title = "Motor fluctuations and dyskinesia in Parkinson's disease",

abstract = "Motor fluctuations and dyskinesia are common complications of long-term levodopa therapy. The neural and molecular mechanisms underlying their development are partially understood. A variety of clinical strategies may reduce the unpredictability of motor fluctuations and reduce their impact. Prevention of these complications remains an elusive goal.",

keywords = "Levodopa, Levodopa-induced dyskinesia, Motor fluctuations, Parkinson's disease",

author = "Nutt, {John G.}",

note = "Funding Information: Preparation of this manuscript is supported in part by the National Parkinson's Foundation and by NIH grant 5 R01 NS21062–14. This manuscript was initially published as a syllabus for the American Academy of Neurology 1999 Annual Meeting. ",

year = "2001",

doi = "10.1016/S1353-8020(01)00024-4",

language = "English (US)",

volume = "8",

pages = "101--108",

journal = "Parkinsonism and Related Disorders",

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publisher = "Elsevier BV",

number = "2",

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TY - JOUR

T1 - Motor fluctuations and dyskinesia in Parkinson's disease

AU - Nutt, John G.

N1 - Funding Information: Preparation of this manuscript is supported in part by the National Parkinson's Foundation and by NIH grant 5 R01 NS21062–14. This manuscript was initially published as a syllabus for the American Academy of Neurology 1999 Annual Meeting.

PY - 2001

Y1 - 2001

N2 - Motor fluctuations and dyskinesia are common complications of long-term levodopa therapy. The neural and molecular mechanisms underlying their development are partially understood. A variety of clinical strategies may reduce the unpredictability of motor fluctuations and reduce their impact. Prevention of these complications remains an elusive goal.

AB - Motor fluctuations and dyskinesia are common complications of long-term levodopa therapy. The neural and molecular mechanisms underlying their development are partially understood. A variety of clinical strategies may reduce the unpredictability of motor fluctuations and reduce their impact. Prevention of these complications remains an elusive goal.

KW - Levodopa

KW - Levodopa-induced dyskinesia

KW - Motor fluctuations

KW - Parkinson's disease

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U2 - 10.1016/S1353-8020(01)00024-4

DO - 10.1016/S1353-8020(01)00024-4

M3 - Article

C2 - 11489675

AN - SCOPUS:0034905501

SN - 1353-8020

VL - 8

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EP - 108

JO - Parkinsonism and Related Disorders

JF - Parkinsonism and Related Disorders

IS - 2

ER -

Motor fluctuations and dyskinesia in Parkinson's disease

Abstract

Keywords

ASJC Scopus subject areas

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