Motor cortex stimulation for enhancement of recovery after stroke: Case report

Jeffrey A. Brown, Helmi Lutsep, Steven C. Cramer, Martin Weinand

Research output: Contribution to journalArticle

98 Citations (Scopus)

Abstract

We present a case report of a 65-year-old patient who had a subcortical infarct and a right spastic hemiparesis that occurred 19 months before being treated with an investigational therapy consisting of low frequency subthreshold epidural motor cortex electrical stimulation delivered during structured occupational therapy repeated daily for three weeks. Before treatment the patient's affected arm rested in a flexion posture and he was unable to flex or extend the fingers. After three weeks of treatment, the resting tone of his arm had improved and he was able to grasp a pen and write letters. The Fugl-Meyer motor scale score improved from 36 to 46 and this improvement was sustained for four weeks after the conclusion of rehabilitation therapy. This is the first patient to be entered into a randomized clinical feasibility and safety study assessing functional improvement in stroke patients treated with epidural cortical stimulation concurrent with occupational therapy (an investigational therapy).

Original languageEnglish (US)
Pages (from-to)815-818
Number of pages4
JournalNeurological Research
Volume25
Issue number8
DOIs
StatePublished - Dec 2003

Fingerprint

Motor Cortex
Stroke
Investigational Therapies
Occupational Therapy
Arm
Muscle Spasticity
Feasibility Studies
Paresis
Posture
Electric Stimulation
Fingers
Therapeutics
Rehabilitation
Safety

Keywords

  • Electrical stimulation
  • Motor cortex
  • Rehabilitation
  • Stroke

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Motor cortex stimulation for enhancement of recovery after stroke : Case report. / Brown, Jeffrey A.; Lutsep, Helmi; Cramer, Steven C.; Weinand, Martin.

In: Neurological Research, Vol. 25, No. 8, 12.2003, p. 815-818.

Research output: Contribution to journalArticle

Brown, Jeffrey A. ; Lutsep, Helmi ; Cramer, Steven C. ; Weinand, Martin. / Motor cortex stimulation for enhancement of recovery after stroke : Case report. In: Neurological Research. 2003 ; Vol. 25, No. 8. pp. 815-818.
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