Monte Carlo modeling of pigmented lesions

Daniel Gareau, Steven Jacques, James Krueger

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Colors observed in clinical dermoscopy are critical to diagnosis but the mechanisms that lead to the spectral components of diffuse reflectance are more than meets the eye: combinations of the absorption and scattering spectra of the biomolecules as well as the a structural effect of skin anatomy. We modeled diffuse remittance from skin based on histopathology. The optical properties of the tissue types were based on the relevant chromophores and scatterers. The resulting spectral images mimic the appearance of pigmented lesions quite well when the morphology is mathematically derived but limited when based on histopathology, raising interesting questions about the interaction between various wavelengths with various pathological anatomical features.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
PublisherSPIE
Volume8926
ISBN (Print)9780819498397
DOIs
StatePublished - 2014
EventPhotonic Therapeutics and Diagnostics X - San Francisco, CA, United States
Duration: Feb 1 2014Feb 2 2014

Other

OtherPhotonic Therapeutics and Diagnostics X
CountryUnited States
CitySan Francisco, CA
Period2/1/142/2/14

Fingerprint

skin (anatomy)
lesions
Skin
Dermoscopy
Biomolecules
Chromophores
scattering
chromophores
Anatomy
Optical properties
Color
Economics
Scattering
Tissue
absorption spectra
reflectance
color
optical properties
Wavelength
wavelengths

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Gareau, D., Jacques, S., & Krueger, J. (2014). Monte Carlo modeling of pigmented lesions. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8926). [89260V] SPIE. https://doi.org/10.1117/12.2040473

Monte Carlo modeling of pigmented lesions. / Gareau, Daniel; Jacques, Steven; Krueger, James.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8926 SPIE, 2014. 89260V.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gareau, D, Jacques, S & Krueger, J 2014, Monte Carlo modeling of pigmented lesions. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8926, 89260V, SPIE, Photonic Therapeutics and Diagnostics X, San Francisco, CA, United States, 2/1/14. https://doi.org/10.1117/12.2040473
Gareau D, Jacques S, Krueger J. Monte Carlo modeling of pigmented lesions. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8926. SPIE. 2014. 89260V https://doi.org/10.1117/12.2040473
Gareau, Daniel ; Jacques, Steven ; Krueger, James. / Monte Carlo modeling of pigmented lesions. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8926 SPIE, 2014.
@inproceedings{a6607925e16a4be8ae552478ca0f4b67,
title = "Monte Carlo modeling of pigmented lesions",
abstract = "Colors observed in clinical dermoscopy are critical to diagnosis but the mechanisms that lead to the spectral components of diffuse reflectance are more than meets the eye: combinations of the absorption and scattering spectra of the biomolecules as well as the a structural effect of skin anatomy. We modeled diffuse remittance from skin based on histopathology. The optical properties of the tissue types were based on the relevant chromophores and scatterers. The resulting spectral images mimic the appearance of pigmented lesions quite well when the morphology is mathematically derived but limited when based on histopathology, raising interesting questions about the interaction between various wavelengths with various pathological anatomical features.",
author = "Daniel Gareau and Steven Jacques and James Krueger",
year = "2014",
doi = "10.1117/12.2040473",
language = "English (US)",
isbn = "9780819498397",
volume = "8926",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",

}

TY - GEN

T1 - Monte Carlo modeling of pigmented lesions

AU - Gareau, Daniel

AU - Jacques, Steven

AU - Krueger, James

PY - 2014

Y1 - 2014

N2 - Colors observed in clinical dermoscopy are critical to diagnosis but the mechanisms that lead to the spectral components of diffuse reflectance are more than meets the eye: combinations of the absorption and scattering spectra of the biomolecules as well as the a structural effect of skin anatomy. We modeled diffuse remittance from skin based on histopathology. The optical properties of the tissue types were based on the relevant chromophores and scatterers. The resulting spectral images mimic the appearance of pigmented lesions quite well when the morphology is mathematically derived but limited when based on histopathology, raising interesting questions about the interaction between various wavelengths with various pathological anatomical features.

AB - Colors observed in clinical dermoscopy are critical to diagnosis but the mechanisms that lead to the spectral components of diffuse reflectance are more than meets the eye: combinations of the absorption and scattering spectra of the biomolecules as well as the a structural effect of skin anatomy. We modeled diffuse remittance from skin based on histopathology. The optical properties of the tissue types were based on the relevant chromophores and scatterers. The resulting spectral images mimic the appearance of pigmented lesions quite well when the morphology is mathematically derived but limited when based on histopathology, raising interesting questions about the interaction between various wavelengths with various pathological anatomical features.

UR - http://www.scopus.com/inward/record.url?scp=84897482922&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84897482922&partnerID=8YFLogxK

U2 - 10.1117/12.2040473

DO - 10.1117/12.2040473

M3 - Conference contribution

AN - SCOPUS:84897482922

SN - 9780819498397

VL - 8926

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

PB - SPIE

ER -